Patient with relapsing-remitting multiple sclerosis diagnosed with familial Mediterranean fever – case report Case report

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Marcelina Jeziorko
Mariusz Kuriański
Katarzyna Zub-Kasprzyk
Stanisław Rusek

Abstract

A patient with multiple sclerosis symptoms which started at 18 years of age and who received immunomodulating treatment initially with interferon β-1a, and subsequently with dimethyl fumarate, presented recurring fever of unknown origin. Serum inflammation markers were negative. Because of those symptoms the patient underwent extensive diagnostics which revealed several non-specific abnormalities. Multiple sclerosis treatment was temporarily halted. Corticosteroids and immunosuppressants lead to partial improvement of the patient’s condition. Eventually the patient was referred to genetic testing which showed genetic predisposition towards familial Mediterranean fever, and colchicine treatment was initiated.

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References

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