In vitro fertilization procedure – role in application progesterone Case report
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Abstract
Progesterone is a hormone necessary for the secretory transformation of the endometrium, which determines the implantation of the embryo and the maintenance of early pregnancy. Supporting the luteal phase with gestagens after embryo transfer is one of the stages of the in vitro fertilization procedure. The combination of progesterone administered sublingually and vaginally provides optimal concentrations for achieving pregnancy during this procedure.
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Polak, G. (2024). In vitro fertilization procedure – role in application progesterone. Medycyna Faktow (J EBM), 17(1(62), 142-145. https://doi.org/10.24292/01.MF.0124.22
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References
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2. Andersen CY, Ezcurra D. Human steroidogenesis: implications for controlled ovarian stimulation with exogenous gonadotropins. Reprod Biol Endocrinol. 2014; 12: 128.
3. Johnson MH. A short history of in vitro fertilization (IVF). Int J Dev Biol. 2019; 63: 83-92.
4. Polak G. Monofolikularna indukcja jajeczkowania gonadotropinami. In: Laudański P (ed). Endokrynologia ginekologiczna i rozrodczość. Najczęstsze problemy. PZWL Wydawnictwo Lekarskie, Warszawa 2023: 10-9.
5. Radwan M. Zapłodnienie pozaustrojowe. In: Radwan J, Wołczyński S (ed). Niepłodność i rozród wspomagany. Termedia, Poznań 2011: 179-210.
6. Pabuccu R, Akar ME. Luteal phase support in assisted reproductive technology. Curr Opin Obstet Gynecol. 2005; 17: 277-81.
7. van der Linden M, Buckingham K, Farquhar C et al. Luteal phase support for assisted reproduction cycles. Cochrane Database Syst Rev. 2015; 7: CD009154.
8. De Ziegler D, Bulletti C, De Monstier B et al. The first uterine pass effect. Ann N Y Acad Sci. 1997; 828: 291-9.
9. Kurzawa R, Czyżyk A, Kuczyński W et al. Stanowisko grupy ekspertów dotyczące wsparcia fazy lutealnej w przypadku technik rozrodu. Med Prakt Ginekol Położ. 2020; 5: 3-11.
10. Venetis CA, Mol BW, Kolibianakis EM. Low as well as high serum P4 levels in the early and mid-luteal phase reduce the chance of a live birth following IVF treatment with fresh embryo transfer: where is the evidence? Hum Reprod. 2018; 33: 2312-3.