Valproic acid in the practice of a psychiatrist. Application in various clinical situations Case report
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Published:
Jun 20, 2022
Keywords:
valproic acid, valproate, bipolar disorder, epilepsy, psychiatry
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Abstract
The article provides basic information on the mechanism of action, effectiveness and restrictions in the use of valproic acid and its derivatives in everyday clinical practice in psychiatry and neurology. In order to illustrate the possible uses of the drug, in accordance with the applicable legal restrictions and recommendations, and at the same time showing the possible benefits of treatment, in the article two clinical cases of patients treated with valproic acid derivatives are presented.
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How to Cite
Antosik-Wójcińska , A. Z. (2022). Valproic acid in the practice of a psychiatrist. Application in various clinical situations. Medycyna Faktow (J EBM), 15(2(55), 262-264. https://doi.org/10.24292/01.MF.0222.22
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References
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2. Andrade C. Major congenital malformations associated with exposure to antiepileptic drugs during pregnancy. J Clin Psychiatry. 2018; 79(4): 18f12449.
3. Veroniki AA, Rios P, Cogo E et al. Comparative safety of antiepileptic drugs for neurological development in children exposed during pregnancy and breast feeding: a systematic review and network meta-analysis. BMJ Open. 2017; 7(7): e017248.
4. Rybakowski J, Cubała WJ, Gałecki P et al. Rekomendacje Polskiego Towarzystwa Psychiatrycznego dotyczące leczenia zaburzeń afektywnych u kobiet w wieku rozrodczym. Część II: Choroba afektywna dwubiegunowa. Psychiatr Pol. 2019; 53(2): 263-76.
5. Gaudio M, Konstantara E, Joy M et al. Valproate prescription to women of childbearing age in English primary care: repeated cross-sectional analyses and retrospective cohort study. BMC Pregnancy Childbirth. 2022; 22(73).
6. Ananthavarathan P. A systematic review and meta-analysis of the efficacy and safety of sodium valproate for „off-label” indications in mental health. J Neurol Neurosurg Psychiatry. 2014; 85: e3.
7. Horowitz E, Bergman LC, Ashkenazy C et al. Off-label use of sodium valproate for schizophrenia. PLoS One. 2014; 9(3): e92573.