Citalopram and its place in clinical practice Case report
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Published:
Jun 20, 2022
Keywords:
citalopram, depression, antidepressants, adverse effects
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Abstract
Citalopram represents one of selective serotonin reuptake inhibitors. It has been registered for the treatment of major depression. However, several studies also indicate its potential use in the treatment of certain anxiety disorders and obsessive-compulsive disorder. It should be noted that the use of citalopram in some clinical situations might be the optimal treatment. This article provides a history of three patients, in whom the use of citalopram appeared to be an effective approach to the treatment of depression that allowed to avoid potential adverse effects associated with antidepressants. These case reports were presented in a broader context of existing evidence in the field of pharmacotherapy of depression.
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How to Cite
Misiak, B. (2022). Citalopram and its place in clinical practice. Medycyna Faktow (J EBM), 15(2(55), 250-254. https://doi.org/10.24292/01.MF.0222.20
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References
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8. Serretti A, Mandelli L. Antidepressants and body weight: A comprehensive review and meta-analysis. J Clin Psychiatry. 2010; 71(10): 1259-72.
9. Goodwin GM, Price J, De Bodinat C et al. Emotional blunting with antidepressant treatments: A survey among depressed patients. J Affect Disord. 2017; 221: 31-5.
10. Read J, Cartwright C, Gibson K. Adverse emotional and interpersonal effects reported by 1829 New Zealanders while taking antidepressants. Psychiatry Res. 2014; 216(1): 67-73.
11. Ma H, Cai M, Wang H. Emotional Blunting in Patients With Major Depressive Disorder: A Brief Non-systematic Review of Current Research. Front Psychiatry. 2021; 12: 792960.
12. Rosenblat JD, Simon GE, Sachs GS et al. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019; 243: 116-20.
13. Serretti A, Chiesa A. Treatment-emergent sexual dysfunction related to antidepressants: A meta-analysis. J Clin Psychopharmacol. 2009; 29(3): 259-66.
14. Bijlsma EY, Chan JSW, Olivier B et al. Sexual side effects of serotonergic antidepressants: Mediated by inhibition of serotonin on central dopamine release? Pharmacol Biochem Behav. 2014; 121: 88-101.
15. Reichenpfader U, Gartlehner G, Morgan LC et al. Sexual dysfunction associated with second-generation antidepressants in patients with major depressive disorder: Results from a systematic review with network meta-analysis. Drug Saf. 2014; 37(1): 19-31.
16. Taylor MJ, Rudkin L, Bullemor-Day P et al. Strategies for managing sexual dysfunction induced by antidepressant medication. Cochrane Database Syst Rev. 2013; 5: CD003382.
2. Bennett S, Thomas AJ. Depression and dementia: Cause, consequence or coincidence? Maturitas. 2014; 79(2): 184-90.
3. Raffaele R, Vecchio I, Giammona G et al. Citalopram in the treatment of depression in the elderly. Arch Gerontol Geriatr 2002; 8: 303-8.
4. Rocca P, Calvarese P, Faggiano F et al. Citalopram versus sertraline in late-life nonmajor clinically significant depression: A 1-year follow-up clinical trial. J Clin Psychiatry. 2005; 66(3): 360-9.
5. Steiner AJ, Recacho J, Vanle B et al. Quality of life, functioning, and depressive symptom severity in older adults with major depressive disorder treated with citalopram in the STARD study. J Clin Psychiatry. 2017; 78(7): 897-903.
6. Czernikiewicz A, Horoch T. Citalopram – lek antydepresyjny z grupy SSRI odkryty na nowo. Psychiatria. 2020; 17(3): 130-3.
7. McCarrell JL, Bailey TA, Duncan NA et al. A review of citalopram dose restrictions in the treatment of neuropsychiatric disorders in older adults. Ment Heal Clin. 2019; 9(4): 280-6.
8. Serretti A, Mandelli L. Antidepressants and body weight: A comprehensive review and meta-analysis. J Clin Psychiatry. 2010; 71(10): 1259-72.
9. Goodwin GM, Price J, De Bodinat C et al. Emotional blunting with antidepressant treatments: A survey among depressed patients. J Affect Disord. 2017; 221: 31-5.
10. Read J, Cartwright C, Gibson K. Adverse emotional and interpersonal effects reported by 1829 New Zealanders while taking antidepressants. Psychiatry Res. 2014; 216(1): 67-73.
11. Ma H, Cai M, Wang H. Emotional Blunting in Patients With Major Depressive Disorder: A Brief Non-systematic Review of Current Research. Front Psychiatry. 2021; 12: 792960.
12. Rosenblat JD, Simon GE, Sachs GS et al. Treatment effectiveness and tolerability outcomes that are most important to individuals with bipolar and unipolar depression. J Affect Disord. 2019; 243: 116-20.
13. Serretti A, Chiesa A. Treatment-emergent sexual dysfunction related to antidepressants: A meta-analysis. J Clin Psychopharmacol. 2009; 29(3): 259-66.
14. Bijlsma EY, Chan JSW, Olivier B et al. Sexual side effects of serotonergic antidepressants: Mediated by inhibition of serotonin on central dopamine release? Pharmacol Biochem Behav. 2014; 121: 88-101.
15. Reichenpfader U, Gartlehner G, Morgan LC et al. Sexual dysfunction associated with second-generation antidepressants in patients with major depressive disorder: Results from a systematic review with network meta-analysis. Drug Saf. 2014; 37(1): 19-31.
16. Taylor MJ, Rudkin L, Bullemor-Day P et al. Strategies for managing sexual dysfunction induced by antidepressant medication. Cochrane Database Syst Rev. 2013; 5: CD003382.