Commentary to: Kane et al. Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early- -Phase Schizophrenia: A Randomized Clinical Trial Commentary

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Adam Wichniak

Abstract

Kane et al. proved that long-acting injection of aripiprazole reduces the risk of hospitalization by 44%. In the group of patients treated with long-acting injections, at least one hospitalization during the follow-up period occurred in 22% of patients, in the group receiving standard therapy it was 36% of patients. This means that in a group of 7 patients, long-acting injections saved one more person from hospitalization than standard treatment.

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How to Cite
Wichniak , A. (2022). Commentary to: Kane et al. Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early- -Phase Schizophrenia: A Randomized Clinical Trial. Medycyna Faktow (J EBM), 15(2(55), 184-187. https://doi.org/10.24292/01.MF.0222.10
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References

1. Leucht S, Tardy M, Komossa K et al. Antipsychotic drugs versus placebo for relapse prevention in schizophrenia: a systematic review and meta-analysis. Lancet. 2012; 379(9831): 2063-71.
2. Tiihonen J, Haukka J, Taylor M et al. A nationwide cohort study of oral and depot antipsychotics after first hospitalization for schizophrenia. Am J Psychiatry. 2011; 168(6): 603-9.
3. Agid O, Arenovich T, Sajeev G et al. An algorithm-based approach to first-episode schizophrenia: response rates over 3 prospective antipsychotic trials with a retrospective data analysis. J Clin Psychiatry. 2011; 72(11): 1439-44.
4. Kane JM, Schooler NR, Marcy P et al. Effect of Long-Acting Injectable Antipsychotics vs Usual Care on Time to First Hospitalization in Early- -Phase Schizophrenia: A Randomized Clinical Trial. JAMA Psychiatry. 2020; 77(12): 1217-24.