W poszukiwaniu źródeł – rola flory jelitowej w zdrowiu i chorobie. Część I Artykuł przeglądowy
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Opublikowane:
wrz 30, 2015
Słowa kluczowe:
transfer flory jelitowej, mikrobiom jelitowy, kolonizacja jelita
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Abstrakt
Coraz więcej danych wskazuje, że skład mikroflory jelitowej może wpływać na procesy istotne dla rozwoju stwardnienia rozsianego, a także innych chorób autoimmunizacyjnych. W artykule przedstawiono aktualne poglądy dotyczące roli fizjologicznej flory jelitowej w funkcjonowaniu ludzkiego organizmu ze szczególnym uwzględnieniem układu odpornościowego oraz ochrony przed kolonizacją jelita przez bakterie patogenne.
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Bibliografia
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10. Ubeda C., Bucci V., Caballero S. et al.: Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization. Infection and Immunity 2013; 81(3): 965-973.
11. van Nood E., Vrieze A., Nieuwdorp M. et al.: Duodenal infusion of donor feces for recurrent Clostridium difficile. The New England Journal of Medicine 2013; 368(5): 407-415.
2. Jandhyala S.M., Talukdar R., Subramanyam C. et al.: Role of the normal gut microbiota. World Journal of Gastroenterology 2015; 21(29): 8787-8803.
3. Ji B., Nielsen J.: From next-generation sequencing to systematic modeling of the gut microbiome. Frontiers in Genetics 2015; 6: 219.
4. Rosenbaum M., Knight R., Leibel R.L.: The gut microbiota in human energy homeostasis and obesity. Trends in endocrinology and metabolism. TEM 2015 [in press, doi: 10.1016/j.tem.2015.07.002].
5. Peterson L.W., Artis D.: Intestinal epithelial cells: regulators of barrier function and immune homeostasis. Nature reviews. Immunology 2014; 14(3): 141-53.
6. Brown E.M., Sadarangani M., Finlay B.B.: The role of the immune system in governing host-microbe interactions in the intestine. Nature Immunology 2013; 14(7): 660-667.
7. Thijm H.A., van der Waaij D.: The effect of three frequently applied antibiotics on the colonization resistance of the digestive tract of mice. The Journal of Hygiene 1979; 82(3): 397-405.
8. Taur Y., Xavier J.B., Lipuma L. et al.: Intestinal domination and the risk of bacteremia in patients undergoing allogeneic hematopoietic stem cell transplantation. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America 2012; 55(7): 905-914.
9. Biliński J., Marchel H., Rusicka P. et al.: Assessment of bacterial gut colonization prior to allogeneic stem cell transplantation as a tool for prediction of systemic infections during early postHSCT period. Bone Marrow Transplant. 2014; 49(S): 101.
10. Ubeda C., Bucci V., Caballero S. et al.: Intestinal microbiota containing Barnesiella species cures vancomycin-resistant Enterococcus faecium colonization. Infection and Immunity 2013; 81(3): 965-973.
11. van Nood E., Vrieze A., Nieuwdorp M. et al.: Duodenal infusion of donor feces for recurrent Clostridium difficile. The New England Journal of Medicine 2013; 368(5): 407-415.