Wazodylatacyjne β-adrenolityki w leczeniu nadciśnienia tętniczego – przykład nebiwololu Artykuł przeglądowy

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Paweł Balsam
Marcin Grabowski

Abstrakt

W terapii nadciśnienia tętniczego dysponujemy pięcioma podstawowymi grupami leków: β-adrenolitykami, antagonistami wapnia, inhibitorami enzymu konwertującego angiotensynę, antagonistami receptorów dla angiotensyny i diuretykami. W skład każdej z tych grup wchodzi co najmniej kilka cząsteczek, które mimo podobnego głównego mechanizmu działania różnią się między sobą w zakresie dodatkowych właściwości. Dodatkowe cechy cząsteczek pozwalają spersonalizować terapię hipotensyjną w zależności od profilu pacjenta. W przypadku β-adrenolityków cząsteczką o dodatkowych właściwościach jest nebiwolol. Mimo że lek obniża ciśnienie tętnicze w podobnym stopniu jak konwencjonalne β-adrenolityki i inne leki hipotensyjne, dodatkowo działa naczyniorozszerzająco za pośrednictwem tlenku azotu.

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Balsam , P., & Grabowski , M. (2014). Wazodylatacyjne β-adrenolityki w leczeniu nadciśnienia tętniczego – przykład nebiwololu. Medycyna Faktów , 7(4(25), 85-91. Pobrano z https://journalsmededu.pl/index.php/jebm/article/view/2344
Dział
Artykuły

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