Reasons to use 5% lidocaine patch Review article
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Abstract
This article discusses the problem of peripheral localized neuropathic pain. One of the therapeutic choices in this condition is 5% lidocaine patches. Local treatment with lidocaine is characterized by direct action at the site of pain, which minimizes systemic side effects and drug interactions, as well as low absorption into the systemic circulation (1–5% of the dose), which translates into a better safety profile. 5% lidocaine patches are registered for the treatment of postherpetic neuralgia, but clinical and observational studies also indicate their effectiveness in diabetic polyneuropathy, posttraumatic neuropathy or carpal tunnel syndrome.
Expert recommendations, including International Association for the Study of Pain Neuropathic Pain Special Interest Group and European Federation of Neurological Societies, indicate 5% lidocaine patches as a second-line drug in peripheral neuropathic pain, and even first-line in the elderly and with multimorbidity, due to the limited possibility of using systemic drugs in these patient groups.
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