Threatened miscarriage – use and role of progesterone Case report
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Published:
Dec 31, 2024
Keywords:
miscarriage, threatened miscarriage, progesterone, dydrogesterone, diabetes mellitus, vaginal spotting
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Abstract
A method to increase the chances of delivery in patients with threatened miscarriage is to use progesterone. This method has been used for many years, but results of the studies do not allow to state clearly whether it is effective or not. The latest results suggest that the effectiveness of progesterone in this group of patients depends on many factors, the most important of which seems to be the number of previous miscarriages. The paper presents examples of assessing the validity of the use of progesterone.
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How to Cite
Huras, H. (2024). Threatened miscarriage – use and role of progesterone. Medycyna Faktow (J EBM), 17(4(65), 561-564. https://doi.org/10.24292/01.MF.0424.20
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References
1. Hasan R, Baird DD, Herring AH et al. Association between first-trimester vaginal bleeding and miscarriage. Obstet Gynecol. 2009; 114: 860-7.
2. Dede FS, Ulucay U, Kose MF et al. Fetal loss in threatened abortion after demonstration of fetal cardiac activity in a low socioeconomic population. J Obstet Gynaecol. 2010; 30: 622-5.
3. Duan L, Yan D, Zeng W et al. Predictive power progesterone combined with beta human chorionic gonadotropin measurements in the outcome of threatened miscarriage. Arch Gynecol Obstet. 2011; 283: 431-5.
4. Li L, Zhang Y, Tan H et al. Effect of progestogen for women with threatened miscarriage: a systematic review and meta-analysis. BJOG. 2020; 127(9): 1055-63.
5. Wang XX, Luo Q, Bai W-P. Efficacy of progesterone on threatened miscarriage: Difference in drug types J Obstet Gynaecol Res. 2019; 45(4): 794-802.
6. Kryvopustor OS, Dosenko VE. Progesteron receptor gene polymorphism as genetic risk factor of threatened abortion. Fiziol Zh (1994) 2016; 62(6): 60-4.
7. Bahia W, Finan RR, Al-Mutawa M et al. Genetic variation in the progesterone receptor gene and susceptibility to recurrent pregnancy loss: a case-control study. BJOG. 2018; 125(6): 729-35.
2. Dede FS, Ulucay U, Kose MF et al. Fetal loss in threatened abortion after demonstration of fetal cardiac activity in a low socioeconomic population. J Obstet Gynaecol. 2010; 30: 622-5.
3. Duan L, Yan D, Zeng W et al. Predictive power progesterone combined with beta human chorionic gonadotropin measurements in the outcome of threatened miscarriage. Arch Gynecol Obstet. 2011; 283: 431-5.
4. Li L, Zhang Y, Tan H et al. Effect of progestogen for women with threatened miscarriage: a systematic review and meta-analysis. BJOG. 2020; 127(9): 1055-63.
5. Wang XX, Luo Q, Bai W-P. Efficacy of progesterone on threatened miscarriage: Difference in drug types J Obstet Gynaecol Res. 2019; 45(4): 794-802.
6. Kryvopustor OS, Dosenko VE. Progesteron receptor gene polymorphism as genetic risk factor of threatened abortion. Fiziol Zh (1994) 2016; 62(6): 60-4.
7. Bahia W, Finan RR, Al-Mutawa M et al. Genetic variation in the progesterone receptor gene and susceptibility to recurrent pregnancy loss: a case-control study. BJOG. 2018; 125(6): 729-35.