Nutrition as an element of treatment and wound healing Review article
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Published:
Jun 30, 2024
Keywords:
diet, nutrition, inflammation, wound healing, collagen, regeneration, antioxidants
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Abstract
Diet is an important element of treatment supporting the wound healing process, but malnutrition can have a significant impact for the regeneration process. Foods rich in nutrients (especially protein and unsaturated fatty acids) and additionally containing numerous microelements, they ensure an adequate level of nutrition and, as a result, support the process wound healing. It is particularly important to ensure an adequate supply of vitamins and minerals (such as vitamins A, C, E and zinc and selenium), because it determines the optimal course of the tissue regeneration process due to the participation of these nutrients in collagen synthesis and subsequent cross-linking, as well as the formation of new blood vessels.
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Jurek, J. M. (2024). Nutrition as an element of treatment and wound healing. Medycyna Faktow (J EBM), 17(2(63), 188-194. https://doi.org/10.24292/01.MF.0224.03
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References
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14. Duarte S, Arango D, Parihar A et al. Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function. Int J Mol Sci. 2013; 14(9): 17664-79.
15. Daher GS, Choi KY, Wells JW et al. A Systematic Review of Oral Nutritional Supplement and Wound Healing. Ann Otol Rhinol Laryngol. 2022; 131(12): 1358-68.
16. Cereda E, Klersy C, Serioli M et al; OligoElement Sore Trial Study Group. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. Ann Intern Med. 2015; 162(3): 167-74. Erratum in: Ann Intern Med. 2015; 163(12): 964.
17. Munoz N, Posthauer ME. Nutrition Essentials: Pressure Injury Prevention and Healing for Adults. Adv Skin Wound Care. 2021; 34(3): 166-67.
18. Kucharzewski, Szkiler E, Krasowski G et al. Algorytmy i wytyczne postępowania terapeutycznego w ranach trudno gojących się. Forum Leczenia Ran. 2020; 1(3): 95-116.
2. Ghaly P, Iliopoulos J, Ahmad M. The role of nutrition in wound healing: an overview. Br J Nurs. 2021; 30(5): S38-S42.
3. Singer AJ, Clark RA. Cutaneous wound healing. N Engl J Med. 1999; 341(10): 738-46.
4. Seth I, Lim B, Cevik J et al. Impact of nutrition on skin wound healing and aesthetic outcomes: A comprehensive narrative review. JPRAS Open. 2024; 39: 291-302.
5. Barchitta M, Maugeri A, Favara G et al. Nutrition and Wound Healing: An Overview Focusing on the Beneficial Effects of Curcumin. Int J Mol Sci. 2019; 20(5): 1119.
6. Bartoszewicz M, Banasiewicz T, Bielecki K et al. Zasady postępowania miejscowego i ogólnego w ranach/owrzodzeniach przewlekłych objętych procesem infekcji. Forum Zakażeń. 2019; 10(1): 1-30.
7. Thevi T, Abas AL, Rajan M. The effects of vitamin C on wound healing – Systematic review. Indian Journal of Surgery. 2024; 1: 1-7.
8. Razzaghi R, Pidar F, Momen-Heravi M et al. Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial. Biol Trace Elem Res. 2018; 181(2): 207-15.
9. Heo JS. Selenium-Stimulated Exosomes Enhance Wound Healing by Modulating Inflammation and Angiogenesis. Int J Mol Sci. 2022; 23(19): 11543.
10. Pompeo M. Misconceptions about protein requirements for wound healing: results of a prospective study. Ostomy Wound Manage. 2007; 53(8): 30-2, 34, 36-38 passim.
11. Lim R, Barker G, Wall CA et al. Dietary phytophenols curcumin, naringenin and apigenin reduce infection-induced inflammatory and contractile pathways in human placenta, foetal membranes and myometrium. Mol Hum Reprod. 2013; 19(7): 451-62.
12. Cannataro R, Fazio A, La Torre C et al. Polyphenols in the Mediterranean Diet: From Dietary Sources to microRNA Modulation. Antioxidants (Basel). 2021; 10(2): 328.
13. Park HY, Kim GY, Choi YH. Naringenin attenuates the release of pro-inflammatory mediators from lipopoly-saccharide-stimulated BV2 microglia by inactivating nuclear factor-κB and inhibiting mitogen-activated protein kinases. Int J Mol Med. 2012; 30(1): 204-10.
14. Duarte S, Arango D, Parihar A et al. Apigenin protects endothelial cells from lipopolysaccharide (LPS)-induced inflammation by decreasing caspase-3 activation and modulating mitochondrial function. Int J Mol Sci. 2013; 14(9): 17664-79.
15. Daher GS, Choi KY, Wells JW et al. A Systematic Review of Oral Nutritional Supplement and Wound Healing. Ann Otol Rhinol Laryngol. 2022; 131(12): 1358-68.
16. Cereda E, Klersy C, Serioli M et al; OligoElement Sore Trial Study Group. A nutritional formula enriched with arginine, zinc, and antioxidants for the healing of pressure ulcers: a randomized trial. Ann Intern Med. 2015; 162(3): 167-74. Erratum in: Ann Intern Med. 2015; 163(12): 964.
17. Munoz N, Posthauer ME. Nutrition Essentials: Pressure Injury Prevention and Healing for Adults. Adv Skin Wound Care. 2021; 34(3): 166-67.
18. Kucharzewski, Szkiler E, Krasowski G et al. Algorytmy i wytyczne postępowania terapeutycznego w ranach trudno gojących się. Forum Leczenia Ran. 2020; 1(3): 95-116.