Prevention and treatment of vitamin D deficiency with cholecalciferol in doses of 7,000 j.m. and 30,000 j.m. Review article
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Abstract
The criteria for vitamin D deficiency, i.e. 25(OH)D <20 ng/ml, and concentrations considered optimal (≥30–50 ng/ml), as well as epidemiological data, indicated the need to conduct preventive and therapeutic schedules for Poland. For obese people, for patients chronically treated with drugs affecting vitamin D metabolism (e.g. anticonvulsants, glucocorticosteroids, antiretroviral drugs, etc.), patients with malabsorption syndromes (e.g. cystic fibrosis, nonspecific intestinal inflammation, bariatric surgery, radiation enteritis), with liver failure, chronic kidney disease, osteomalacia, with chronic musculoskeletal pain, as well as with hyperparathyroidism, autoimmune diseases, for the elderly (>65 years), especially in seniors with a history of falls or low-energy fractures (osteoporosis), schemes for the prevention and treatment of vitamin D deficiency have been proposed using 7,000 j.m. and 30,000 j.m. of cholecalciferol in daily or cumulative supply, taking into account safety.
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References
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