Early use of progesterone for the prevention of some obstetric complications Case report
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Published:
Dec 31, 2023
Keywords:
pregnancy, threatened miscarriage, prevention, progesterone, preeclampsia
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Abstract
Vaginal progesterone reduces the risk of miscarriage in women who have experienced similar complications. The best results can be obtained by using this form during the first trimester of pregnancy. Very promising results were also obtained in the prevention of preeclampsia.
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How to Cite
Kwiatkowski, S. (2023). Early use of progesterone for the prevention of some obstetric complications. Medycyna Faktow (J EBM), 16(4(61), 410-413. https://doi.org/10.24292/01.MF.0423.19
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References
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7. Melo P, Devall A, Shennan AH et al. Vaginal micronised progesterone for the prevention of hypertensive disorders of pregnancy: A systematic review and meta-analysis. BJOG. 2023: http://doi.org/10.1111/1471-0528.17705.
8. Coomarasamy A, Devall AJ, Cheed V et al. A randomized trial of progesterone in women with bleeding in early pregnancy. N Engl J Med. 2019; 380(19): 1815-24.
9. Coomarasamy A, Williams H, Truchanowicz E et al. A randomized trial of progesterone in women with recurrent miscarriages. N Engl J Med. 2015; 373(22): 2141-8.
10. McLindon LA, James G, Beckmann MM et al. Progesterone for women with threatened miscarriage (STOP trial): a placebo-controlled randomized clinical trial. Hum Reprod. 2023; 38(4): 560-8.
11. ESHRE Guideline Group on RPL; Bender Atik R, Christiansen OB et al. ESHRE guideline: recurrent pregnancy loss. Hum Reprod Open. 2018; 2018(2): hoy004. http://doi.org/10.1093/hropen/hoy004
12. ESHRE Guideline Group on RPL; Bender Atik R, Christiansen OB et al. ESHRE guideline: recurrent pregnancy loss: an update in 2022. Hum Reprod Open. 2023; 2023(1): hoad002. http://doi.org/10.1093/hropen/hoad002.
13. Hennessy M, Dennehy R, Meaney S et al. Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review. Reprod Biomed Online. 2021; 42(6): 1146-71. http://doi.org/10.1016/j.rbmo.2021.02.014.
14. Bulletti C, Bulletti FM, Sciorio R et al. Progesterone: The Key Factor of the Beginning of Life. Int J Mol Sci. 2022; 23(22): 14138. http://doi.org/10.3390/ijms232214138.
15. Wise J. NICE recommends progesterone to prevent early miscarriage. BMJ. 2021; 375: n2896. http://doi.org/10.1136/bmj.n2896.
2. Sitruk-Ware R, El-Etr M. Progesterone and related progestins: potential new health benefits. Climacteric. 2013; 16(suppl 1): 69-78. http://doi.org/10.3109/13697137.2013.802556.
3. Motomura K, Miller D, Galaz J et al. The effects of progesterone on immune cellular function at the maternal-fetal interface and in maternalcirculation. J Steroid Biochem Mol Biol. 2023; 229: 106254. http://doi.org/10.1016/j.jsbmb.2023.106254.
4. Choi SJ. Use of progesterone supplement therapy for prevention of preterm birth: review of literatures. Obstet Gynecol Sci. 2017; 60(5): 405-20. http://doi.org/10.5468/ogs.2017.60.5.405.
5. Rolnik DL, Wright D, Poon LC et al. Aspirin versus placebo in pregnancies at high risk for preterm preeclampsia. N Engl J Med. 2017; 377(7): 613-22.
6. Ghesquiere L, Guerby P, Marchant I et al. Comparing aspirin 75 to 81 mg vs 150 to 162 mg for prevention of preterm preeclampsia: systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2023; 5(7): 101000. http://doi.org/10.1016/j.ajogmf.2023.101000.
7. Melo P, Devall A, Shennan AH et al. Vaginal micronised progesterone for the prevention of hypertensive disorders of pregnancy: A systematic review and meta-analysis. BJOG. 2023: http://doi.org/10.1111/1471-0528.17705.
8. Coomarasamy A, Devall AJ, Cheed V et al. A randomized trial of progesterone in women with bleeding in early pregnancy. N Engl J Med. 2019; 380(19): 1815-24.
9. Coomarasamy A, Williams H, Truchanowicz E et al. A randomized trial of progesterone in women with recurrent miscarriages. N Engl J Med. 2015; 373(22): 2141-8.
10. McLindon LA, James G, Beckmann MM et al. Progesterone for women with threatened miscarriage (STOP trial): a placebo-controlled randomized clinical trial. Hum Reprod. 2023; 38(4): 560-8.
11. ESHRE Guideline Group on RPL; Bender Atik R, Christiansen OB et al. ESHRE guideline: recurrent pregnancy loss. Hum Reprod Open. 2018; 2018(2): hoy004. http://doi.org/10.1093/hropen/hoy004
12. ESHRE Guideline Group on RPL; Bender Atik R, Christiansen OB et al. ESHRE guideline: recurrent pregnancy loss: an update in 2022. Hum Reprod Open. 2023; 2023(1): hoad002. http://doi.org/10.1093/hropen/hoad002.
13. Hennessy M, Dennehy R, Meaney S et al. Clinical practice guidelines for recurrent miscarriage in high-income countries: a systematic review. Reprod Biomed Online. 2021; 42(6): 1146-71. http://doi.org/10.1016/j.rbmo.2021.02.014.
14. Bulletti C, Bulletti FM, Sciorio R et al. Progesterone: The Key Factor of the Beginning of Life. Int J Mol Sci. 2022; 23(22): 14138. http://doi.org/10.3390/ijms232214138.
15. Wise J. NICE recommends progesterone to prevent early miscarriage. BMJ. 2021; 375: n2896. http://doi.org/10.1136/bmj.n2896.