Effective treatment of pain and fever in children – case reports Case report
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Published:
Dec 31, 2023
Keywords:
pain, fever, ibuprofen, paracetamol, combined therapy, children
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Abstract
Pain and fever are the most common reasons for parents and children to visit a pediatrician. Pain is an unpleasant, subjective sensory and emotional experience. We treat pain and fever in all children in whom we have correctly identified and interpreted them, and our actions are primarily intended to reduce the patient’s discomfort and anxiety. The basic drugs for treating pain and relieving fever are paracetamol and ibuprofen as non-steroidal anti-inflammatory drug, and their effectiveness has been confirmed in many clinical studies. If monotherapy at optimal doses does not effectively reduce pain and fever, it is worth using combined treatment (ibuprofen + paracetamol in one drug).
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How to Cite
Sybilski, A. J. (2023). Effective treatment of pain and fever in children – case reports. Medycyna Faktow (J EBM), 16(4(61), 404-409. https://doi.org/10.24292/01.MF.0423.18
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References
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13. Luo S, Ran M, Luo Q et al. Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial. Paediatr Drugs. 2017; 19(5): 479-86.
14. Charde V, Sanklecha M, Rajan P et al. Comparing the Efficacy of Paracetamol, Ibuprofen, and a Combination of the Two Drugs in Relieving Pain and Fever in the Pediatric Age Group: A Prospective Observational Study. Cureus. 2023; 15(10): e46907.
15. Parri N, Silvagni D, Chiarugi A et al. Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT). Ital J Pediatr. 2023; 49(1): 36.
2. Amaechi O, Huffman MM, Featherstone K. Pharmacologic Therapy for Acute Pain. Am Fam Physician. 2021; 104(1): 63-72.
3. Doniec Z, Jackowska T, Sybilski A et al. FEVER in children – recommendations for primary care doctors – FEVER COMPASS. Fam Med Prim Care Rev. 2021; 23: 99-115.
4. Sahib El-Radhi A, Carroll J, Klein N et al. Measurement of Body Temperature. In: Sahib El-Radhi A, Carroll J, Klein N (ed). Clinical Manual of Fever in Children. Springer, Cham, Switzerland 2018: 69-84.
5. Woroń J. Farmakoterapia gorączki. Farmakologia leków przeciwgorączkowych. In: Sybilski AJ, Woroń J, Życińska K (ed). Gorączka. Przyczyny, diagnostyka, leczenie. Medical Education, Warszawa 2021: 67-78.
6. NICE Guideline Updates Team (UK). Fever in under 5s: assessment and initial management. London: National Institute for Health and Care Excellence (UK); 2019 Nov. (NICE Guideline, No. 143).
7. Dipiro JT, Talbert RL, Mee GC et al. Pharmacotherapy: A Pathophysiologic Approach, 10e. McGraw Hill, New York 2020.
8. Martindale. The Complete Drug Reference. Pharmaceutical Press, London 2020.
9. Paul IM, Walson PD. Acetaminophen and ibuprofen in the treatment of pediatric fever: a narrative review. Curr Med Res Opin. 2021; 37(8): 1363-75.
10. Muśko M, Sznitowska M. Postacie leków pediatrycznych. Część I. Wymagania i podstawowe problemy – dawkowanie, połykanie, smak. Farm Pol. 2010; 66(3): 215-20.
11. Hryniewicz W, Albrecht P, Radzikowski A (ed). Rekomendacje postępowania w pozaszpitalnych zakażeniach układu oddechowego. Narodowy Instytut Leków, Warszawa 2016.
12. Pokorna-Kałwak D, Jazienicka-Kiełb A. Ear infections in children. Supportive treatment with antibiotic therapy. Lekarz POZ. 2023; 9(1): 43-9.
13. Luo S, Ran M, Luo Q et al. Alternating Acetaminophen and Ibuprofen versus Monotherapies in Improvements of Distress and Reducing Refractory Fever in Febrile Children: A Randomized Controlled Trial. Paediatr Drugs. 2017; 19(5): 479-86.
14. Charde V, Sanklecha M, Rajan P et al. Comparing the Efficacy of Paracetamol, Ibuprofen, and a Combination of the Two Drugs in Relieving Pain and Fever in the Pediatric Age Group: A Prospective Observational Study. Cureus. 2023; 15(10): e46907.
15. Parri N, Silvagni D, Chiarugi A et al. Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT). Ital J Pediatr. 2023; 49(1): 36.