Sodium picosulphate or polyethylene glycol before elective colonoscopy in outpatients? A systematic review and meta-analysis Discussion
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Published:
Nov 30, 2023
Keywords:
colorectal cancer, colonoscopy, bowel preparation, polyethylene glycol, sodium picosulphate
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Abstract
This paper summarizes and discusses a meta-analysis of 16 randomized trials comparing the efficacy of two pharmacological agents [sodium picosulfate magnesium citrate (SPMC) or polyethylene glycol (PEG)] used in bowel preparation prior to elective colonoscopy in adult outpatients. The results of the analysis showed the superiority of SPMC over PEG in terms of the degree of bowel clearance, patient tolerance and incidence of side effects. There were no differences between PEG and SPMC in the detection of polyps and adenomas.
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How to Cite
Kamiński, M. F. (2023). Sodium picosulphate or polyethylene glycol before elective colonoscopy in outpatients? A systematic review and meta-analysis. Medycyna Faktow (J EBM), 16(3(60), 357-361. https://doi.org/10.24292/01.MF.0323.14
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References
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2. Rex DK, Petrini JL, Baron TH et al. Quality indicators for colonoscopy. Am J Gastroenterol. 2006; 101(4): 873-85.
3. Hassan C, East J, Radaelli F et al. Bowel preparation for colonoscopy: European Society of Gastrointestinal Endoscopy (ESGE) Guideline – Update 2019. Endoscopy. 2019; 51(8): 775-94.
4. Clark BT, Protiva P, Nagar A et al. Quantification of Adequate Bowel Preparation for Screening or Surveillance Colonoscopy in Men. Gastroenterology. 2016; 150(2): 396-405; quiz e14-5.
5. Rocha RSP, Ribeiro IB, de Moura DTH et al. Sodium picosulphate or polyethylene glycol before elective colonoscopy in outpatients? A systematic review and meta-analysis. World J Gastrointest Endosc. 2018; 10(12): 422-41.
6. Bucci C, Rotondano G, Hassan C et al. Optimal bowel cleansing for colonoscopy: split the dose! A series of meta-analyses of controlled studies. Gastrointest Endosc. 2014; 80(4): 566-76.e2.
7. Pohl J, Halphen M, Kloess HR et al. Impact of the quality of bowel cleansing on the efficacy of colonic cancer screening: a prospective, randomized, blinded study. PLoS One. 2015; 10: e0126067.
8. Bechtold ML, Mir F, Puli SR et al. Optimizing bowel preparation for colonoscopy: a guide to enhance quality of visualization. Ann Gastroenterol. 2016; 29(2): 137-46.