FFR supported coronary angioplasty in patients with multivessel coronary disease – the FAME study results Review article
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Published:
Jun 30, 2009
Keywords:
percutaneus coronary intervention, fractional flow reserve (FFR), drug eluting stent (DES), multivessel coronary artery disease
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Abstract
The number of patients with multivessel coronary artery disease treated with percutaneus coronary interventions is still increasing. However, it is unclear whether revascularization of all angiografically significant lesions can be beneficial. FFR (fractional flow reserve) is a method which can assess physiologically significant stenotic lesions. The result of FAME study shows that routine measurement of FFR in patients with multivessel coronary artery disease, who are undergoing PCI with drug eluting stent significantly reduces the rate of cardiovascular complication.
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Janiszewski , M., & Chmielewski , M. (2009). FFR supported coronary angioplasty in patients with multivessel coronary disease – the FAME study results. Medycyna Faktow (J EBM), 2(2(3), 62-65. Retrieved from https://journalsmededu.pl/index.php/jebm/article/view/2668
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References
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4. Shaw L.J., Berman D.S., Maron D.J. et al.: Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. Circulation 2008; 117: 1283-91.
5. Fischer J.J., Samady H., McPherson J.A. et al.: Comparison between visual assessment and quantitative angiography versus fractional flow reserve for native coronary narrowings of moderate severity. Am. J. Cardiol. 2002; 90: 210-5.
6. Pijls N.H., De Bruyne B., Peels K. et al.: Measurement of fractional flow reserve to assess the functional severity of coronary artery stenoses. N. Engl. J. Med. 1996; 334: 1703-8.
2. Serruys P.W., Morice M.C., Kappetein A.P. et al.: Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery disease. N. Engl. J. Med. 2009 Mar. 5; 360(10): 961-72.
3. Boden W.E., O’Rourke R.A., Teo K.K. et al.: Optimal medical therapy with or without PCI for stable coronary disease. N. Engl. J. Med. 2007; 356: 1503-16.
4. Shaw L.J., Berman D.S., Maron D.J. et al.: Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. Circulation 2008; 117: 1283-91.
5. Fischer J.J., Samady H., McPherson J.A. et al.: Comparison between visual assessment and quantitative angiography versus fractional flow reserve for native coronary narrowings of moderate severity. Am. J. Cardiol. 2002; 90: 210-5.
6. Pijls N.H., De Bruyne B., Peels K. et al.: Measurement of fractional flow reserve to assess the functional severity of coronary artery stenoses. N. Engl. J. Med. 1996; 334: 1703-8.