The inhibition of renin-angiotensin-aldosterone system and myocardial infarction – what treatment according to EBM enables the best prevention? Review article

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Agnieszka Wsół
Marek Kuch

Abstract

The renin-angiotensin-aldosterone system plays an important role in the regulation of cardiovascular functions under physiological and pathological conditions. Initially the effectiveness of treatment with angiotensin-converting enzyme inhibitors (ACE-I) and angiotensin II receptor antagonists (ARB) in the pharmacotherapy of coronary artery disease was taught to be equal. However the results of large randomized clinical trials indicated that ACE-I vs ARB are more effective in the prevention of coronary artery disease and in the light of the current standards of European and American Cardiac Societies (ESC, AHA/ACC) should be an alternative method of treatment in case of intolerance of ACE-I.

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How to Cite
Wsół, A., & Kuch , M. (2010). The inhibition of renin-angiotensin-aldosterone system and myocardial infarction – what treatment according to EBM enables the best prevention?. Medycyna Faktow (J EBM), 3(2(7), 23-34. Retrieved from https://journalsmededu.pl/index.php/jebm/article/view/2601
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References

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