Sitagliptin and its position in contemporary management of type 2 diabetes mellitus Review article
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Published:
Nov 22, 2022
Keywords:
sitagliptin, DPP-4 inhibitors, incretins, type 2 diabetes mellitus
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Abstract
DPP-4 inhibitors are class of oral agents registered for management of type 2 diabetes mellitus. They improve glucose control by decreasing HbA1c without risk of hypoglycaemia as well as weight gain. They are well tolerated and demonstrate durability. Sitagliptin is the most commonly used agent of the class and it’s cardiovascular safety profile was demonstrated in TECOS trial.
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How to Cite
Dzida , G. (2022). Sitagliptin and its position in contemporary management of type 2 diabetes mellitus. Medycyna Faktow (J EBM), 15(4(57), 407-409. https://doi.org/10.24292/01.MF.0422.5
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References
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2. Scott LJ . Sitagliptin: A Review in Type 2 Diabetes. Drugs. 2017; 77: 209-24. http://doi.org/10.1007/s40265-016-0686-9.
3. Green JB, Bethel MA , Armstrong PW et al. Effect of Sitagliptin on Cardiovascular Outcomes in Type 2 Diabetes. N Engl J Med. 2015; 373: 232-42. http://doi.org/10.1056/NEJMoa1501352.
4. Ou SM, Shih CJ , Chao PW et al. Effects on Clinical Outcomes of Adding Dipeptidyl Peptidase-4 Inhibitors Versus Sulfonylureas to Metformin Therapy in Patients With Type 2 Diabetes Mellitus. Ann Intern Med. 2015; 163: 663-72. http://doi.org/10.7326/M15-0308.
5. Kaneko M, Narukawa M. Meta-Analysis of Dipeptidyl Peptidase-4 Inhibitors Use and Cardiovascular Risk in Patients with Type 2 Diabetes Mellitus. Diabetes Res Clin Pract. 2016; 116: 171-82. http://doi.org/10.1016/j.diabres.2016.04.012.
6. Araszkiewicz A, Bandurska-Stankiewicz E, Borys S et al. 2022 Guidelines on the Management of Patients with Diabetes. A Position of Diabetes Poland. Curr Top Diabetes. 2022; 2: 1-134.