Effects of rosuvastatin therapy on atherosclerotic plaques Review article
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Published:
Dec 31, 2015
Keywords:
rosuvastatin, low-density lipoprotein cholesterol, atherosclerotic plaque
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Abstract
Statin-mediated cholesterol lowering improves clinical outcomes. Stabilization and regression of the atherosclerotic plaque play an important role in preventing cardiovascular disease. The favorable effects of statins extend across a range of levels of low-density lipoprotein (LDL) cholesterol, with no apparent lower threshold for a benefit. At the same time, imaging trials have shown that intensive statin regimens slow the progression of coronary atherosclerosis and may even result in disease regression in some patients.
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Postuła , M., & Kosior , D. (2015). Effects of rosuvastatin therapy on atherosclerotic plaques. Medycyna Faktow (J EBM), 8(4(29), 45-49. Retrieved from https://journalsmededu.pl/index.php/jebm/article/view/2281
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References
1. Cannon C.P., Braunwald E., McCabe C.H. et al.: Intensive versus moderate lipid lowering with statins after acute coronary syndromes. N. Engl. J. Med. 2004; 350: 1495-1504.
2. Nissen S.E., Nicholls S.J., Sipahi I. et al.: Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006; 295: 1556-1565.
3. Nicholls S.J., Ballantyne C.M., Barter P.J.: Effect of two intensive statin regimens on progression of coronary disease. N. Engl. J. Med. 2011; 365: 2078-2087.
4. Friedman M., Byers S.O., Rosenman R.H.: Resolution of aortic atherosclerotic infiltration in the rabbit by phosphatide infusion. Proc. Soc. Exp. Biol. Med. 1957; 95(3): 586-588.
5. Nicholls S.J., Hsu A., Wolski K. et al.: Intravascular ultrasound-derived measures of coronary atherosclerotic plaque burden and clinical outcome. J. Am. Coll. Cardiol. 2010; 55(21): 2399-2407.
6. Jang I.K., Tearney G.J., MacNeill B. et al.: In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography. Circulation 2005; 111(12): 1551-1555.
7. Stone G.W., Maehara A., Lansky A.J. et al.: A prospective natural-history study of coronary atherosclerosis. N. Engl. J. Med. 2011; 364: 226-235.
8. Jaross W., Neumeister V., Lattke P., Schuh D.: Determination of cholesterol in atherosclerotic plaques using near infrared diffuse reflection spectroscopy. Atherosclerosis 1999; 147(2): 327-337.
9. Moreno P.R., Lodder R.A., Purushothaman K.R. et al.: Detection of lipid pool, thin fibrous cap, and inflammatory cells in human aortic atherosclerotic plaques by near-infrared spectroscopy. Circulation 2002; 105(8): 923-927.
10. Wang J., Geng Y.J., Guo B. et al.: Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques. J. Am. Coll. Cardiol. 2002; 39(8): 1305-1313.
11. Crisby M., Nordin-Fredriksson G., Shah P.K. et al.: Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-933.
12. Takayama T., Hiro T., Yamagishi M. et al.: Effect of rosuvastatin on coronary atheroma in stable coronary artery disease: multicenter coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS). Circ. J. 2009; 73(11): 2110-2117.
13. Crouse J.R., Raichlen J.S., Riley W.A. et al.; METEOR Study Group: Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial. JAMA 2007; 297: 1344-1353.
14. Nicholls S.J., Ballantyne C.M., Barter P.J. et al.: Effect of two intensive statin regimens on progression of coronary disease. N. Engl. J. Med. 2011; 365: 2078-2087.
15. Puri R., Nissen S.E., Ballantyne C.M. et al.: Factors underlying regression of coronary atheroma with potent statin therapy. Eur. Heart J. 2013; 34(24): 1818-1825.
16. Puri R., Nissen S.E., Shao M. et al.: Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy. Eur. Heart J. 2013; 34(41): 3182-3190.
17. Gao W.Q., Feng Q.Z., Li Y.X. et al.: Systematic study of the effects of lowering low-density lipoprotein-cholesterol on regression of coronary atherosclerotic plaques using intravascular ultrasound. BMC Cardiovasc. Disord. 2014; 14: 60.
2. Nissen S.E., Nicholls S.J., Sipahi I. et al.: Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 2006; 295: 1556-1565.
3. Nicholls S.J., Ballantyne C.M., Barter P.J.: Effect of two intensive statin regimens on progression of coronary disease. N. Engl. J. Med. 2011; 365: 2078-2087.
4. Friedman M., Byers S.O., Rosenman R.H.: Resolution of aortic atherosclerotic infiltration in the rabbit by phosphatide infusion. Proc. Soc. Exp. Biol. Med. 1957; 95(3): 586-588.
5. Nicholls S.J., Hsu A., Wolski K. et al.: Intravascular ultrasound-derived measures of coronary atherosclerotic plaque burden and clinical outcome. J. Am. Coll. Cardiol. 2010; 55(21): 2399-2407.
6. Jang I.K., Tearney G.J., MacNeill B. et al.: In vivo characterization of coronary atherosclerotic plaque by use of optical coherence tomography. Circulation 2005; 111(12): 1551-1555.
7. Stone G.W., Maehara A., Lansky A.J. et al.: A prospective natural-history study of coronary atherosclerosis. N. Engl. J. Med. 2011; 364: 226-235.
8. Jaross W., Neumeister V., Lattke P., Schuh D.: Determination of cholesterol in atherosclerotic plaques using near infrared diffuse reflection spectroscopy. Atherosclerosis 1999; 147(2): 327-337.
9. Moreno P.R., Lodder R.A., Purushothaman K.R. et al.: Detection of lipid pool, thin fibrous cap, and inflammatory cells in human aortic atherosclerotic plaques by near-infrared spectroscopy. Circulation 2002; 105(8): 923-927.
10. Wang J., Geng Y.J., Guo B. et al.: Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques. J. Am. Coll. Cardiol. 2002; 39(8): 1305-1313.
11. Crisby M., Nordin-Fredriksson G., Shah P.K. et al.: Pravastatin treatment increases collagen content and decreases lipid content, inflammation, metalloproteinases, and cell death in human carotid plaques: implications for plaque stabilization. Circulation 2001; 103: 926-933.
12. Takayama T., Hiro T., Yamagishi M. et al.: Effect of rosuvastatin on coronary atheroma in stable coronary artery disease: multicenter coronary atherosclerosis study measuring effects of rosuvastatin using intravascular ultrasound in Japanese subjects (COSMOS). Circ. J. 2009; 73(11): 2110-2117.
13. Crouse J.R., Raichlen J.S., Riley W.A. et al.; METEOR Study Group: Effect of rosuvastatin on progression of carotid intima-media thickness in low-risk individuals with subclinical atherosclerosis: the METEOR Trial. JAMA 2007; 297: 1344-1353.
14. Nicholls S.J., Ballantyne C.M., Barter P.J. et al.: Effect of two intensive statin regimens on progression of coronary disease. N. Engl. J. Med. 2011; 365: 2078-2087.
15. Puri R., Nissen S.E., Ballantyne C.M. et al.: Factors underlying regression of coronary atheroma with potent statin therapy. Eur. Heart J. 2013; 34(24): 1818-1825.
16. Puri R., Nissen S.E., Shao M. et al.: Coronary atheroma volume and cardiovascular events during maximally intensive statin therapy. Eur. Heart J. 2013; 34(41): 3182-3190.
17. Gao W.Q., Feng Q.Z., Li Y.X. et al.: Systematic study of the effects of lowering low-density lipoprotein-cholesterol on regression of coronary atherosclerotic plaques using intravascular ultrasound. BMC Cardiovasc. Disord. 2014; 14: 60.