Fibrates – role and mechanisms of hypolipemic action Review article

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Piotr Sobieraj
Jacek Lewandowski
Krzysztof Dęmbe
Przemysław Krasnodębski

Abstract

Dyslipidaemias are common cardiovascular risk factor in Poland. Besides statins, fibrates are basic therapeutic agents in management of lipid disorders. Treatment with fibrates, as basal or additional drug, is indicated particularly in dyslipidaemias with elevated serum triglycerides. The mechanism of action is still unknown, but the role of nuclear receptors PPAR is suggested. In the article indications for treatment with fibrates, principles of the drug administration, mechanism of action in connection with physiological function of PPAR family are presented.

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How to Cite
Sobieraj , P., Lewandowski , J., Dęmbe , K., & Krasnodębski , P. (2015). Fibrates – role and mechanisms of hypolipemic action. Medycyna Faktow (J EBM), 8(4(29), 24-30. Retrieved from https://journalsmededu.pl/index.php/jebm/article/view/2279
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