Metoprolol – one drug, seven therapeutic indications Review article
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Abstract
Metoprolol is a cardioselective β-blocker, devoid of internal sympathomimetic activity. It is one of the β-blockers with the most therapeutic indications. In selected indications it is recommended for children over 6 years of age and pregnant women. The sustained release formulation provides a steady therapeutic concentration for 24 h. Metoprolol can be safely used in patients with renal failure.
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Wydra, W., & Kuch , M. (2017). Metoprolol – one drug, seven therapeutic indications. Medycyna Faktow (J EBM), 10(2(35), 146-151. Retrieved from https://journalsmededu.pl/index.php/jebm/article/view/2156
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3. COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group: Early intravenous then oral metoprolol in 45,852 patients with acute myocardial infarction: randomised placebo-controlled trial. Lancet 2005; 366(9497): 1622-1632.
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5. Miller S., Matharu M.S.: Migraine is underdiagnosed and undertreated. The Practitioner 2014; 258(1774): 19-24.
6. Evers S., Afra J., Frese A. et al.: EFNS guideline on the drug treatment of migraine – revised report of an EFNS task force. Eur. J. Neurol. 2009; 16: 968-981.
7. Owecki M.K., Łukasik M., Kozubski W.: Współczesne zasady farmakoterapii migreny. Nowiny Lekarskie 2011; 80(2): 116-125.
8. Loder E., Burch R., Rizzoli P. et al.: The 2012 AHS/AAN Guidelines for Prevention of Episodic Migraine: A Summary and Comparison With Other Recent Clinical Practice Guidelines. Headache 2012; 52: 930-945.
9. Kangasniemi P., Andersen A.R., Andersson P.G. et al.: Classic migraine: effective prophylaxis with metoprolol. Cephalalgia 1987; 7(4): 231-238.
10. Steiner T.J., Joseph R., Hedman C., Rose F.C.: Metoprolol in the prophylaxis of migraine: parallel group comparison with placebo and dos-ranging follow-up. Headache 1988; 28: 15-23.
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