The position of a combination of fluticasone and salmeterol in asthma therapy in the light of the new GINA 2019 guidelines Review article
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Published:
Sep 30, 2019
Keywords:
salmeterol, fluticasone, GINA, asthma
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Abstract
Salmeterol + fluticasone combination in a single inhaler was introduced to the asthma treatment 20 years ago. Since then, it possess the prominent place in asthma and COPD treatment guidelines. Due to safety and efficacy it belongs to first choice asthma treatment from step 3 through 5 in GINA 2019 guidelines. It reduces airway hyperreactivity and increases the number of asthma free-days and the number of days without rescue medication.
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Pawliczak, R. (2019). The position of a combination of fluticasone and salmeterol in asthma therapy in the light of the new GINA 2019 guidelines. Medycyna Faktow (J EBM), 12(3(44), 243-245. https://doi.org/10.24292/01.MF.0319.9
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References
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2. Aubier M., Pieters W.R., Schlösser N.J., Steinmetz K.O.: Salmeterol/fluticasone propionate (50/500 microg) in combination in a Diskus inhaler (Seretide) is effective and safe in the treatment of steroid-dependent asthma. Respir. Med. 1999; 93(12): 876-884.
3. Chapman K.R., Ringdal N., Backer V. et al.: Salmeterol and fluticasone propionate (50/250 microg) administered via combination Diskus inhaler: as effective as when given via separate Diskus inhalers. Can. Respir. J. 1999; 6(1): 45-51.
4. Condemi J.J., Goldstein S., Kalberg C. et al.: The addition of salmeterol to fluticasone propionate versus increasing the dose of fluticasone propionate in patients with persistent asthma. Salmeterol Study Group. Ann. Allergy Asthma Immunol. 1999; 82(4): 383-389.
5. Spencer C.M., Jarvis B.: Salmeterol/fluticasone propionate combination. Drugs 1999; 57(6): 933-940; discussion 941-943.
6. van Noord J.A., Schreurs A., Mol S., Mulder P.: Addition of salmeterol versus doubling the dose of fluticasone propionate in patients with mild to moderate asthma. Thorax 1999; 54(3): 207-212.
7. Bateman E.D., Bousquet J., Busse W.W. et al.: Stability of asthma control with regular treatment: an analysis of the Gaining Optimal Asthma controL (GOAL) study. Allergy 2008; 63(7): 932-938.
8. Lundback B., Rönmark E., Lindberg A. et al.: Asthma control over 3 years in a real-life study. Respir. Med. 2009; 103(3): 348-355.
9. Trautmann M., Banik N., Tews J.T., Jorres R.A.: Efficacy of the combination of fluticasone propionate and salmeterol in patients with moderate persistent asthma within a „real-life” setting. Eur. J. Med. Res. 2007; 12(6): 255-263.
10. Woodcock A.A., Bagdonas A., Boonsawat W. et al.: Improvement in asthma endpoints when aiming for total control: salmeterol/fluticasone propionate versus fluticasone propionate alone. Prim. Care Respir. J. 2007; 16(3): 155-161.
11. Bateman E.D., Clark T.J., Frith L. et al.: Rate of response of individual asthma control measures varies and may overestimate asthma control: an analysis of the goal study. J. Asthma 2007; 44(8): 667-673.
12. Bateman E.D., Bousquet J., Keech M.L. et al.: The correlation between asthma control and health status: the GOAL study. Eur. Respir. J. 2007; 29(1): 56-62.
13. Briggs A.H., Bousquet J., Wallace M.V. et al.: Cost-effectiveness of asthma control: an economic appraisal of the GOAL study. Allergy 2006; 61(5): 531-536.
14. Stoloff S.W., Stempel D.A., Meyer J. et al.: Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies. J. Allergy Clin. Immunol. 2004; 113(2): 245-251.
2. Aubier M., Pieters W.R., Schlösser N.J., Steinmetz K.O.: Salmeterol/fluticasone propionate (50/500 microg) in combination in a Diskus inhaler (Seretide) is effective and safe in the treatment of steroid-dependent asthma. Respir. Med. 1999; 93(12): 876-884.
3. Chapman K.R., Ringdal N., Backer V. et al.: Salmeterol and fluticasone propionate (50/250 microg) administered via combination Diskus inhaler: as effective as when given via separate Diskus inhalers. Can. Respir. J. 1999; 6(1): 45-51.
4. Condemi J.J., Goldstein S., Kalberg C. et al.: The addition of salmeterol to fluticasone propionate versus increasing the dose of fluticasone propionate in patients with persistent asthma. Salmeterol Study Group. Ann. Allergy Asthma Immunol. 1999; 82(4): 383-389.
5. Spencer C.M., Jarvis B.: Salmeterol/fluticasone propionate combination. Drugs 1999; 57(6): 933-940; discussion 941-943.
6. van Noord J.A., Schreurs A., Mol S., Mulder P.: Addition of salmeterol versus doubling the dose of fluticasone propionate in patients with mild to moderate asthma. Thorax 1999; 54(3): 207-212.
7. Bateman E.D., Bousquet J., Busse W.W. et al.: Stability of asthma control with regular treatment: an analysis of the Gaining Optimal Asthma controL (GOAL) study. Allergy 2008; 63(7): 932-938.
8. Lundback B., Rönmark E., Lindberg A. et al.: Asthma control over 3 years in a real-life study. Respir. Med. 2009; 103(3): 348-355.
9. Trautmann M., Banik N., Tews J.T., Jorres R.A.: Efficacy of the combination of fluticasone propionate and salmeterol in patients with moderate persistent asthma within a „real-life” setting. Eur. J. Med. Res. 2007; 12(6): 255-263.
10. Woodcock A.A., Bagdonas A., Boonsawat W. et al.: Improvement in asthma endpoints when aiming for total control: salmeterol/fluticasone propionate versus fluticasone propionate alone. Prim. Care Respir. J. 2007; 16(3): 155-161.
11. Bateman E.D., Clark T.J., Frith L. et al.: Rate of response of individual asthma control measures varies and may overestimate asthma control: an analysis of the goal study. J. Asthma 2007; 44(8): 667-673.
12. Bateman E.D., Bousquet J., Keech M.L. et al.: The correlation between asthma control and health status: the GOAL study. Eur. Respir. J. 2007; 29(1): 56-62.
13. Briggs A.H., Bousquet J., Wallace M.V. et al.: Cost-effectiveness of asthma control: an economic appraisal of the GOAL study. Allergy 2006; 61(5): 531-536.
14. Stoloff S.W., Stempel D.A., Meyer J. et al.: Improved refill persistence with fluticasone propionate and salmeterol in a single inhaler compared with other controller therapies. J. Allergy Clin. Immunol. 2004; 113(2): 245-251.