Naproxen – a multifunctional drug in the light of current research and reports Review article
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Published:
Sep 30, 2021
Keywords:
NSAID, SARS-CoV-2, pain, rheumatic diseases, chronic diseases
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Abstract
The therapeutic effects of naproxen and its unique pharmacological properties allows it to use not only in the practice of primary care physicians, but also in specialist clinics. Naproxen is effective in relieving musculoskeletal pain of various origins, and additionally has anti-inflammatory and antipyretic properties. This enables its effective use in chronic diseases such as: RA, OA, AS, as well as for effective reduction of symptoms of classic infections, especially viral infections, reducing pain in muscles, joints, head and lowering fever.
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How to Cite
Sarzyńska-Długosz, I., & Sapilak , B. (2021). Naproxen – a multifunctional drug in the light of current research and reports. Medycyna Faktow (J EBM), 14(3(52), 310-314. https://doi.org/10.24292/01.MF.0321.14
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References
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11. Athamneh T, Amin A, Benke E et al. Pulmonary drug delivery with aerogels: engineering of alginate and alginate-hyaluronic acid microspheres. Pharm Dev Technol. 2021; 26(5): 509-21. http://doi.org/10.1080/10837450.2021.1888979.
2. Brune K, Patrignani P. New insights into the use of currently available non-steroidal anti-inflammatory drugs. J Pain Res. 2015; 8: 105-18. http://doi.org/10.2147/JPR.S75160.
3. Kiani P, Scholey A, Dahl TA et al. In Vitro Assessment of the Antiviral Activity of Ketotifen, Indomethacin and Naproxen, Alone and in Combination, against SARS-CoV-2. Viruses. 2021; 13(4): 558. http://doi.org/10.3390/v13040558.
4. Terrier O, Dilly S, Pizzorno A et al. Antiviral Properties of the NSAID Drug Naproxen Targeting the Nucleoprotein of SARS-CoV-2 Coronavirus. Molecules. 2021; 26(9): 2593. http://doi.org/10.3390/molecules26092593.
5. Robb CT, Goepp M, Rossi AG et al. Non-steroidal anti-inflammatory drugs, prostaglandins, and COVID-19. Br J Pharmacol. 2020; 177(21): 4899-920. http://doi.org/10.1111/bph.15206.
6. Chiou WC, Hsu MS, Chen YT et al. Repurposing existing drugs: identification of SARS-CoV-2 3C-like protease inhibitors. J Enzyme Inhib Med Chem. 2021; 36(1): 147-53. http://doi.org/10.1080/14756366.2020.1850710.
7. Weisman S. Naproxen for Post-Operative Pain. J Pharm Pharm Sci. 2021; 24: 62-70. http://doi.org/10.18433/jpps31629.
8. Paglia MDG, Silva MT, Lopes LC et al. Use of corticoids and non-steroidal anti-inflammatories in the treatment of rheumatoid arthritis: Systematic review and network meta-analysis. PLoS One. 2021; 16(4): e0248866. http://doi.org/10.1371/journal.pone.0248866.
9. Zhang H, Wu Y, Lin Z et al. Naproxen for the treatment of neoplastic fever: A PRISMA-compliant systematic review and meta-analysis. Medicine (Baltimore). 2019; 98(22): e15840. http://doi.org/10.1097/MD.0000000000015840.
10. Moideen S, Anver PC, Uvais NA et al. Positive Naproxen Test in Psychogenic Fever. Prim Care Companion CNS Disord. 2021; 23(3): 20l02630. http://doi.org/10.4088/PCC.20l02630.
11. Athamneh T, Amin A, Benke E et al. Pulmonary drug delivery with aerogels: engineering of alginate and alginate-hyaluronic acid microspheres. Pharm Dev Technol. 2021; 26(5): 509-21. http://doi.org/10.1080/10837450.2021.1888979.