Anxiety in cardiology. The use of pregabalin in the treatment of anxiety disorders in patients with cardiovascular diseases Case report
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Published:
Dec 31, 2021
Keywords:
anxiety disorders, myocardial infarction, coronary artery disease, pregabalin
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Abstract
The paper discusses two issues: the multidirectional relationship between the occurrence of anxiety symptoms and cardiovascular diseases, and the influence of the persistently high level of anxiety on the course of cardiological diseases and patient prognosis. In the discussion on the negative health consequences of anxiety disorders, there is emphasized importance of early diagnosis of these disorders and implementation of its treatment. As a starting point there were presented clinical cases of cardiovascular patients in whom developed anxiety disorders. The following sections discuss various aspects of the pharmacological treatment of anxiety disorders, focusing on the possible use of pregabalin in this.
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How to Cite
Antosik-Wójcińska, A. (2021). Anxiety in cardiology. The use of pregabalin in the treatment of anxiety disorders in patients with cardiovascular diseases. Medycyna Faktow (J EBM), 14(4(53), 428-432. https://doi.org/10.24292/01.MF.0421.12
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References
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9. Montgomery S, Chatamra K, Pauer L et al. Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. Br J Psychiatry. 2008; 193: 389-94.
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11. Diaper A, Rich AS, Wilson SJ et al. Changes in cardiovascular function after venlafaxine but not pregabalin in healthy volunteers: a double-blind, placebo-controlled study of orthostatic challenge, blood pressure and heart rate. Hum Psychopharmacol. 2013; 28: 562-75.
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13. Zhang X, Xu H, Zhang Z et al. Efficacy and Safety of Pregabalin for Fibromyalgia in a Population of Chinese Subjects. J Pain Res. 2021; 14: 537-48. http://doi.org/10.2147/JPR.S281483.
14. Hu J, Huang D, Li M et al. Effects of a single dose of preoperative pregabalin and gabapentin for acute postoperative pain: a network meta-analysis of randomized controlled trials. J Pain Res. 2018; 11: 2633-43.
15. Mishriky BM, Waldron NH, Habib AS. Impact of pregabalin on acute and persistent postoperative pain: a systematic review and meta-analysis. Br J Anaesth. 2015; 114(1): 10-31.
16. Kheirabadi D, Safavi MR, Taghvaei M et al. Comparing the prophylactic effects of oral gabapentin, pregabalin, and celecoxib on postoperative pain management in orthopedic surgery of the lower extremity: A double-blind randomized controlled trial. J Res Med Sci. 2020; 25: 9.
17. Zhang D, You G, Yao X. Influence of pregabalin on post-operative pain after laparoscopic cholecystectomy: A meta-analysis of randomised controlled trials. J Minim Access Surg. 2019; 16(2): 99-105.
18. Said AM, Zubovic E, Ha AY et al. Effects of Single-Dose Preoperative Pregabalin on Postoperative Pain and Opioid Consumption in Cleft Orthognathic Surgery. J Craniofac Surg. 2021; 32(2): 517-20.
19. Bech P. Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry. 2007; 40: 163-8.
20. Lydiard RB, Rickels K, Herman B et al. Comparative efficacy of pregabalin and benzodiazepines in treating the psychic and somatic symptoms of generalized anxiety disorder. Int J Neuropsychopharmacol. 2010; 13: 229-41.
2. Baldwin DS, Ajel K, Masdrakis VG et al. Pregabalin for the treatment of generalized anxiety disorder: an update. Neuropsychiatr Dis Treat. 2013; 9: 883-92.
3. Moser DK. “The rust of life”: impact of anxiety on cardiac patients. Am J Crit Care. 2007; 16(4): 361-9.
4. Celano CM, Daunis DJ, Lokko HN et al. Anxiety Disorders and Cardiovascular Disease. Curr Psychiatry Rep. 2016; 18(11): 101.
5. Frasure-Smith N, Lesperance F. Depression and anxiety as predictors of 2-year cardiac events in patients with stable coronary artery disease. Arch Gen Psychiatry. 2008; 65(1): 62-71.
6. Hanssen TA, Nordrehaug JE, Eide GE et al. Anxiety and depression after acute myocardial infarction: an 18-month follow-up study with repeated measures and comparison with a reference population. Eur J Cardiovasc Prev Rehabil. 2009; 16(6): 651-9.
7. Grace SL, Abbey SE, Irvine J et al. Prospective examination of anxiety persistence and its relationship to cardiac symptoms and recurrent cardiac events. Psychother Psychosom. 2004; 73(6): 344-52.
8. Hanssen TA, Nordrehaug JE, Eide GE et al. Anxiety and depression after acute myocardial infarction: an 18-month follow-up study with repeated measures and comparison with a reference population. Eur J Cardiovasc Prev Rehabil. 2009; 16(6): 651-9.
9. Montgomery S, Chatamra K, Pauer L et al. Efficacy and safety of pregabalin in elderly people with generalised anxiety disorder. Br J Psychiatry. 2008; 193: 389-94.
10. Cvjetkovic-Bosnjak M, Soldatovic-Stajic B, Babovic SS et al. Pregabalin versus sertraline in generalized anxiety disorder. An open label study. Eur Rev Med Pharmacol Sci. 2015; 19: 2120-4.
11. Diaper A, Rich AS, Wilson SJ et al. Changes in cardiovascular function after venlafaxine but not pregabalin in healthy volunteers: a double-blind, placebo-controlled study of orthostatic challenge, blood pressure and heart rate. Hum Psychopharmacol. 2013; 28: 562-75.
12. White AT, Light KC, Bateman L et al. Effect of Pregabalin on Cardiovascular Responses to Exercise and Postexercise Pain and Fatigue in Fibromyalgia: A Randomized, Double-Blind, Crossover Pilot Study. Pain Res Treat. 2015; 2015: 136409.
13. Zhang X, Xu H, Zhang Z et al. Efficacy and Safety of Pregabalin for Fibromyalgia in a Population of Chinese Subjects. J Pain Res. 2021; 14: 537-48. http://doi.org/10.2147/JPR.S281483.
14. Hu J, Huang D, Li M et al. Effects of a single dose of preoperative pregabalin and gabapentin for acute postoperative pain: a network meta-analysis of randomized controlled trials. J Pain Res. 2018; 11: 2633-43.
15. Mishriky BM, Waldron NH, Habib AS. Impact of pregabalin on acute and persistent postoperative pain: a systematic review and meta-analysis. Br J Anaesth. 2015; 114(1): 10-31.
16. Kheirabadi D, Safavi MR, Taghvaei M et al. Comparing the prophylactic effects of oral gabapentin, pregabalin, and celecoxib on postoperative pain management in orthopedic surgery of the lower extremity: A double-blind randomized controlled trial. J Res Med Sci. 2020; 25: 9.
17. Zhang D, You G, Yao X. Influence of pregabalin on post-operative pain after laparoscopic cholecystectomy: A meta-analysis of randomised controlled trials. J Minim Access Surg. 2019; 16(2): 99-105.
18. Said AM, Zubovic E, Ha AY et al. Effects of Single-Dose Preoperative Pregabalin on Postoperative Pain and Opioid Consumption in Cleft Orthognathic Surgery. J Craniofac Surg. 2021; 32(2): 517-20.
19. Bech P. Dose-response relationship of pregabalin in patients with generalized anxiety disorder. A pooled analysis of four placebo-controlled trials. Pharmacopsychiatry. 2007; 40: 163-8.
20. Lydiard RB, Rickels K, Herman B et al. Comparative efficacy of pregabalin and benzodiazepines in treating the psychic and somatic symptoms of generalized anxiety disorder. Int J Neuropsychopharmacol. 2010; 13: 229-41.