Komórki NK – rola i udział w zdrowiu i chorobie
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komórki NK, rola w odporności
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Do dziś komórki NK w większości podręczników immunologicznych opisywane są jako komórki biorące udział w inicjowaniu odpowiedzi immunologicznej. W świetle nowych badań NK mają możliwości udziału także w odporności adaptacyjnej, stanowiąc jakby pomost pomiędzy inicjacją a dostosowaniem odpowiedzi immunologicznej.
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Stasiak-Barmuta , A., Alifier , M., Rapiejko , P., Wojdas , A., & Stankiewicz , W. (2009). Komórki NK – rola i udział w zdrowiu i chorobie. Alergoprofil, 5(3), 5-11. Pobrano z https://journalsmededu.pl/index.php/alergoprofil/article/view/148
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
Bibliografia
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3. Arase H., Arase N., Saito T.: Interferon gamma production by natural killer (NK) cells and NK1.1+T cells upon NKR-P1 cross-linking. J. Exp. Med. 1996, 183: 2391-2396.
4. Aspalter R.M., Sewell W.A.C., Dolman K., Farrant J., Webster A.D.B.: Deficiency in circulating natural killer (NK) cell subsets in common variable immunodeficiency and Xlinked agammaglobulinaemia. Clin. Exp. Immunol. 2000, 121: 506-514.
5. Azeredo E.L., De Oliveira-Pinto L.M., Zagne S.M., Cerqueira D.I.S., Nogueira R.M.R., Kubelka C.F.: NK cells, displaying early activation, cytotoxicity and adhesion molecules, are as1. sociated with mild dengue disease. Clin. Exp. Immunol. 2006, 143: 345-356.
6. Bauer S., Groh V., Wu J., Steinle A., Phillips J.H., Lanier L.L., Spies T.: Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999, 285: 727-729.
7. Becker I., Salaiza N., Aguirre M., Delgado J., Carrillo-Carrasco N., Kobeh L.G., Ruiz A., Cervantes R., Torres A.P., Cabrera N., Gonzalez A., Maldonado C., Isibasi A.: Leishmania lipophosphoglycan (LPG) activates NK cells through tolllike receptor-2. Mol. Biochem. Parasitol. 2003, 130: 65-74.
8. Bertone S., Schiavtti F., Bellorno R., Vittale C., Ponte M., Moretta L., Mingari M.C.: Transforming growth factor β-induced expression of CD94/NKG2A inhibitory receptors in human T lymphocytes. Eur. J. Immunol. 1999, 29: 23-29.
9. Braud V.M., Allen D.S.J., O’Callaghan C.A., Söderström K., D’Andrea A., Ogg G.S., Lazetic S., Young N.T., Bell J.I., Phillips J.H.: HLA-E binds to natural killer cell receptor for the nonclassical major histocompatibility complex (MHC) class I molecule Qa-1(b). J. Exp. Med. 1998, 188: 1841-1848.
10. Carson W.E., Fehniger T.A., Haldar S., Eckhert K., Lindemann M.J., Lai C-F., Croce C.M., Baumann H., Caligiuri M.A.: A potential role for interleukin-15 in the regulation of human natural killer cell suvival. J. Clin. Invest. 1997, 99: 937-943.
11. Carson W.E., Giri J.G., Lindemann M.J., Linett M.L., Ahdieh M., Paxton R., Anderson D., Eisenmann J., Grabstein K., Caligiuri M.A.: Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J. Exp. Med. 1994, 180: 1395-1403.
12. Carson W.E., Lindemann M.J., Baiocchi R., Linett M., Tan J.C., Chou C.C., Narula S., Caligiuri M.A.: The functional characterization of interleukin-10 receptor expression on human natural killer cells. Blood 1995, 85: 3577-3585.
13. Cerwenka A., Bakker A.B.H., McClanahan T., Wagner J., Wu J., Phillips J.H., Lanier L.L.: Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice. Immunity 2000, 12: 721-727.
14. Chambers B.J., Salcedo M., Ljunggren H.G.: Triggering of natural killer cells by the costimulatory molecule CD80 (B7-1). Immunity 1996, 5: 311-317.
15. Chambers C.A., Kang J., Wu Y., Held W., Raulet D.H., Allison J.P.: The lymphoproliferative defect in CTLA-4-deficient mice is ameliorated by an inhibitory NK cell receptor. Immunology 2002, 99(12): 4509-4516.
16. Chen X., Armstrong M.A., Li G.: Mesenchymal stem cells in immunoregulation. Immunol. Cell Biol. 2006, 84: 413-421.
17. Colonna M., Moretta A., Vely F., Vivier E.: A high-resolution view of NK-cell receptors: structure and function. Immunol. Today 2000, 21(9): 428-431.
18. Colonna M.: Immunoglobulin superfamily inhibitory receptors: from natural killer cells to antigen presenting cells. Res. Immunol. 1997, 148: 169-171.
19. Cooper M.A., Fehniger T.A., Caligiuri M.A.: The biology of human natural killer-cell subsets. Trends Immunol. 2001, 22: 633-640.
20. Cooper M.A., Fehniger T.A., Ponnappan A., Mahta V., Wewers M.D., Caligiuri M.A.: Interleukin-1β costimulates interferon-γ production by human natural killer cells. Eur. J. Immunol. 2001, 31: 792-801.
21. Cosman D., Mullberg J., Sutherland C.L., Chin W., Armitage R., Fanslow W., Kubin M., Chalupny N.J.: ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 2001, 14: 123-133.
22. D’Andrea A., Chang C., Philips J.H., Lanier L.L.: Regulation of T cell lymphokine production by killer cell inhibitory receptor recognition of self HLA class I alleles. J. Exp. Med. 1996, 184: 789-794.
23. De La Barrera S., Finiasz M., Fink S., Ilarregui J., Alemán M., Olivares L., Franco M.C., Pizzariello G., Del Carmen Sasiain M.: NK cells modulate the cytotoxic activity generated by Mycobacterium leprae-hsp65 in leprosy patients: role of IL-18 and IL-13. Clin. Exp. Immunol. 2004, 135: 105-113.
24. Difenbach A., Jamieson A.M., Liu S.D., Shastri N., Raulet D.H.: Novel ligands for the murine NKG2D receptor: expression by tumor cells and activation of NK cells and macrophages. Nat. Immunol. 2000, 1: 119-126.
25. Difenbach A., Raulet D.H.: Strategies for target cell recognition by natural killer cells. Immunol. Rev. 2001, 181: 170-184.
26. Dimasi N., Biassoni R.: Structural and functional aspects of the Ly49 natural killer cell receptors. Immunol. Cell Biol. 2005, 83: 1-8.
27. Fehniger T.A., Shah M.H., Turner M.J., VanDeusen J.B., Whitman S.P., Cooper M.A., Suzuli K., Wechser M., Goodsaid F., Caligiuri M.A.: Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response. J. Immunol. 1999, 162: 4511-4520.
28. Ferlazzo G., Tsang M.L., Moretta L., Melioli G., Steinman R.M., Munz C.: Human dendritic cells activate resting natural killer (NK) cells and are recognized via the NKp30 receptor by activated NK cells. J. Exp. Med. 2002, 195: 343-51.
29. Fogler W.E., Volker K., McCormick K.L., McCormick K.L., Watanabe M., Ortaldo J.R., Wiltrout R.H.: NK cell infiltration into lung, liver, and subcutaneous B16 melanoma is mediated by VCAM-1/VLA-4 interaction. J. Immunol. 1996, 156(12): 4707-4714.
30. Gerosa F., Baldani-Guerra B., Nisii C., Marchesini V., Carra G., Trinchieri G.: Reciprocal activating interaction between natural killer cells and dendritic cells. J. Exp. Med. 2002, 195: 327-33.
31. Golden-Mason L., Kelly A.M., Doherty D.G., Traynor O., McEntee G., Kelly J., Hegarty J.E., O’Farrelly C.: Hepatic interleuklin 15 (IL-15) expression: implications for local NK/NKT cell homeostasis and development. Clin. Exp. Immunol. 2004, 138: 94-101.
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