Wheat-dependent exercise-induced anaphylaxis in patient with cross – reactivity – case report Case report
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Abstract
The prevalence of food allergy is rising. The diagnosis of food hypersensitivity in adults is difficult due to the frequent occurrence of atypical symptoms and the coexistence of allergy to many allergens. In some patients with food allergy, allergic reactions are more severe if a cofactor is involved. Exercise, alcohol, estrogens, and some drugs such as non-steroidal anti-inflammatory drugs, angiotensin converting enzyme inhibitors, β-blockers, and are the main factors described. Wheat-dependent exercise-induced anaphylaxis is a rare, but potentially severe food allergy exclusively occurring when wheat ingestion is accompanied by augmenting cofactors. Among wheat proteins, ω-5 gliadin is the major allergen. We present an interesting case of a patient diagnosed with wheat-dependent exercise-induced anaphylaxis and oral allergy syndrome resulting from cross-allergy.
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
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