Patient with disseminated malignant tumor of the pancreas. Application of liposomal irinotecan as a new option of palliative treatment Opis przypadku

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Opublikowane: lip 12, 2021
DOI: https://doi.org/10.24292/01.OR.123120721
Słowa kluczowe:
liposomal irinotecan, malignant neoplasm of the pancreas, pancreatic cancer

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Bogumiła Galińska
Clinical Department of Oncology, Chemotherapy and Cancer Immunotherapy, Pomeranian Medical University of Szczecin; Independent Public Clinic Hospital no. 1
Rafał Becht
Clinical Department of Oncology, Chemotherapy and Cancer Immunotherapy, Pomeranian Medical University of Szczecin; Independent Public Clinic Hospital no. 1

Abstrakt

In palliative treatment of pancreatic neoplasms, chemotherapy regimens with gemcitabine, nab-paclitaxel, oxaliplatin, irinotecan, 5-fluorouracil or combinations of these drugs are used. The registration of liposomal irinotecan in the treatment of stage IV disease in patients with progression after gemcitabine creates new options for the treatment choice. The described case concerns a relatively young patient in whom the use of liposomal irinotecan in the registration indication turned out to be a safe and well-tolerated treatment.

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1.
Galińska B, Becht R. Patient with disseminated malignant tumor of the pancreas. Application of liposomal irinotecan as a new option of palliative treatment. OncoReview [Internet]. 12 lipiec 2021 [cytowane 22 listopad 2024];11(3(43):73-6. Dostępne na: https://journalsmededu.pl/index.php/OncoReview/article/view/1518
Numer
Tom 11 Nr 3(43) (2021)
Dział
PERSONALIZED ONCOLOGY
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

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Bibliografia

1. Ducreux M, Cuhna A Sa, Caramella C et al. Cancer of the pancreas: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2015; 25(suppl 5): V56-V68.
2. Zalecenia postępowania diagnostyczno-terapeutycznego w nowotworach złośliwych 2019 r.
3. Wang-Gillam A, Hubner RA, Siveke JT et al. NAPOLI-1 phase 3 study of liposomal irinotecan in metastatic pancreatic cancer: Final overall survival analysis and characteristics of long-term survivors. Eur J Cancer. 2019; 108: 78-87.