https://journalsmededu.pl/index.php/OncoReview/issue/feedOncoReview2024-09-10T18:09:20+02:00Marcin Kuzmamarcin@journalsmededu.plOpen Journal Systems<p>The main area of <em>OncoReview’s </em> scientific mission is the emerging field of interdisciplinary oncology, with particular emphasis on cardio-oncology. Scientific papers published in the journal concern modern diagnostic and therapeutic methods used in this population of patients, as well as all adverse events related to anticancer treatment. Objective assessment of the benefits and risks of new oncological drugs is a unique benefit of the published works. <br><span lang="en-GB"><br></span><span lang="en-GB"><strong>e-ISSN: </strong>2450-6125 <strong> DOI: </strong>10.24292/01.OR<br><br><strong>Indexed in: </strong></span><strong>SCOPUS</strong>: SJR = 0.125; SNIP = 0.099<br><span lang="en-GB"> Polish Journals Master List: <strong>20 points</strong> <br> Index Copernicus: 116.25 <br> Google Scholar<br> Polish Medical Bibliography</span></p> <p> </p>https://journalsmededu.pl/index.php/OncoReview/article/view/3112Drug resistance in breast cancer2024-09-10T18:09:17+02:00Nagesh Madnoorkarnageshmadnoorkar@gmail.comRahul Jainrrj5086@gmail.comRahul Sapatenageshmadnoorkar@gmail.comGagandip Singh Bhamranageshmadnoorkar@gmail.comPooja Thakarenageshmadnoorkar@gmail.com<p><strong>Objective</strong>: The obstacle of resistance throughout breast cancer treatment leads to failure of therapy and progress in the disease. Current developments in our knowledge of the molecular pathways behind resistance to therapies in breast cancer will be covered in this brief review.</p> <p><strong>Materials and methods</strong>: The presented data in this review is gathered from multiple sources such as clinical observations (information about how patients react to systemic treatments), experimental models (data gathered from in vitro and in vivo drug resistance simulation framework), review of genetic alterations and epigenetic changes that contribute to resistance is done through genomic and epigenetic studies. The drug resistance mechanisms: target mutations, novel signaling pathways, modifications to the tumor microenvironment, emerging biomarkers, genetic and epigenetic modifications (targeted gene mutations, modifications in drug transporter expression, activation of signaling pathways).</p> <p><strong>Conclusion</strong>: Ongoing investigations are essential for identifying successful approaches to combat drug resistance in breast cancer. The process of refinement of combining medicines, development of novel targeted treatments, and research into mechanisms that limit drug transport are among the areas of focus.</p>2024-07-10T00:00:00+02:00Copyright (c) 2024 Medical Educationhttps://journalsmededu.pl/index.php/OncoReview/article/view/3109An extremely rare case of atypical fibroxanthoma – case report2024-09-10T18:09:20+02:00Natalia Żaknzak93@gmail.comPatrycja Adamskapatrycja_adamska@op.plAleksandra Błaszczykaleksandra.poczta4@gmail.comBarbara Jaworskabarbaraewajaworska@gmail.comAldona Pażyraaldona.pazyra16@gmail.comNatalia Kusaknatmarielea@gmail.comPaweł Stanickistanicki99@gmail.com<p style="font-weight: 400;">The first clinical case of atypical fibroxanthoma was documented in 1958, and to date, approximately 3,000 patients have been described in the literature with this diagnosis. Furthermore, the recurrence rate or potential for metastasis in atypical fibroxanthoma is estimated to be as low as 2%. It is noteworthy that fibroxanthoma most commonly arises in the head and neck region. Therefore, the clinical case presented here of a patient diagnosed with atypical fibroxanthoma on the left earlobe margin, with suspected disease recurrence after approximately one year, is extremely rare, so we believed it is noticeable to report.</p>2024-07-10T00:00:00+02:00Copyright (c) 2024 Medical Educationhttps://journalsmededu.pl/index.php/OncoReview/article/view/3113Awareness about colorectal cancer among young adults in Poland2024-09-10T18:09:14+02:00Marta FudalejAgata.mormull@gmail.comJulia PikulAgata.mormull@gmail.comAgata Mormulagata.mormull@gmail.comAndrzej DeptałaAgata.mormull@gmail.comAnna Badowska-Kozakiewiczagata.mormull@gmail.com<p><strong>Purpose</strong>: The present study aimed to evaluate the knowledge and awareness level concerning colorectal cancer epidemiology, risk factors, symptoms, and prevention among young people in Poland.</p> <p><strong>Methods</strong>: The knowledge was examined with an anonymous survey between February and March 2021. The data were collected anonymously, and the participation was voluntary. Statistical analysis was performed, and differences were considered significant if the p-value obtained was smaller than the assumed level of significance p ≤0.05.</p> <p><strong>Results</strong>: Respondents were mostly female, living in a city with a population of over 500,000. The results confirmed that education, family/friends’ history of CRC, and a place of residence differentiate knowledge and awareness about CRC.</p> <p><strong>Conclusion</strong>: The study acquired information that might guide educators about knowledge deficits among young people in Poland. The survey results revealed a significant knowledge gap between rural and urban inhabitants as well as between medical and non-medical groups.</p>2024-07-11T00:00:00+02:00Copyright (c) 2024 Medical Education