Apalutamide as a new option for postponing metastatic disease in hormone-resistant patients with biochemical recurrence in prostate cancer Case report

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Bartosz Dąbek

Abstract

Treatment of non-metastatic castration-resistant prostate cancer is a radically new option for cancer patients. Novel anti-hormonal therapy not only improves metastasis free survival but overall survival times and positively impacts quality of life. This case shows how apalutamide lowered tPSA level and postponed metastatic disease.

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How to Cite
1.
Dąbek B. Apalutamide as a new option for postponing metastatic disease in hormone-resistant patients with biochemical recurrence in prostate cancer. OncoReview [Internet]. 2023Apr.1 [cited 2024Nov.22];13(1(49):24-6. Available from: https://journalsmededu.pl/index.php/OncoReview/article/view/2790
Section
SUPPORTIVE CARE IN ONCOLOGY

References

1. Siegel RL, Miller KD, Wagle NS et al. Cancer statistics, 2023. CA Cancer J Clin. 2023; 73(1): 17-48. http://doi.org/10.3322/caac.21763.
2. Smith MR, Saad F, Chowdhury S et al. Apalutamide Treatment and Metastasis-free Survival in Prostate Cancer. N Engl J Med. 2018; 378: 1408-18. http://doi.org/10.1056/NEJMoa1715546.
3. Hussain M, Fizazi K, Saad F et al. Enzalutamide in Men with Nonmetastatic, Castration-Resistant Prostate Cancer. N Engl J Med. 2018; 378: 2465-74.
4. Fizazi K, Shore N, Tammela TL et al. Darolutamide in Nonmetastatic, Castration-Resistant Prostate Cancer. N Engl J Med. 2019; 380: 1235-46. http://doi.org/10.1056/NEJMoa1815671.
5. Hofman MS, Lawrentschuk N, Francis RJ et al. Prostate-specific membrane antigen PET-CT in patients with high-risk prostate cancer before curative- intent surgery or radiotherapy (proPSMA ): A prospective, randomised, multicentre study. Lancet. 2020; 395: 1208-16. http://doi.org/10.1016/S0140-6736(20)30314-7.
6. Afshar-Oromieh A, Holland-Letz T, Giesel FL et al. Diagnostic performance of (68)Ga-PSMA -11 (HBED-CC) PET/CT in patients with recurrent prostate cancer: Evaluation in 1007 patients. Eur J Nucl Med Mol Imaging. 2017; 44: 1258-68. http://doi.org/10.1007/s00259-017-3711-7.