Spectacular efficacy of neoadjuvant chemotherapy in a patient with cervical cancer of IB2 grade according to FIGO 2009 Case report

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Kamila Kaźmierczak
Błażej Nowakowski
Joanna Kufel-Grabowska
Witold Cholewiński

Abstract

The presented case report is an example of a spectacular effect of induction systemic treatment in a patient with locally advanced cervical cancer of IB2 grade according to FIGO 2009 (International Federation of Gynecologist and Obstetrician). The effect of induction chemotherapy (three series in paclitaxel/24 h + cisplatin regimen at an interval of three weeks) was the total metabolic response of the primary tumor and nodal lesions found in FDG-PET/CT (18F-fluorodeoxyglucose – positron emission tomography combined with computed tomography) as well as an image of total regression of the tumor in the obtained postoperative histopathological examination.

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How to Cite
1.
Kaźmierczak K, Nowakowski B, Kufel-Grabowska J, Cholewiński W. Spectacular efficacy of neoadjuvant chemotherapy in a patient with cervical cancer of IB2 grade according to FIGO 2009. OncoReview [Internet]. 2020Jun.30 [cited 2020Oct.30];10(2(38):69-6. Available from: https://journalsmededu.pl/index.php/OncoReview/article/view/1070
Section
GYNECOLOGIC ONCOLOGY

References

1. International Agency for Research on Cancer – IARC, Gobocan 2012. Estimated cancer incidence, mortality and prevalence worldwide 2015. http://globocan.iarc.fr.
2. Wojciechowska U, Didkowska J. Zachorowania i zgony na nowotwory złośliwe w Polsce, Krajowy Rejestr Nowotworów, Centrum Onkologii – Instytut im. Marii Skłodowskiej-Curie. http://onkologia.org.pl/raporty (Access: 3.04.2020).
3. Markowska J, Mądry J. Zarys ginekologii onkologicznej. Vol. 1. Termedia, Poznań 2018: 622-30, 797-8, 736-8.
4. Nowakowski A, Kotarski J. Rak szyjki macicy w Polsce i na świecie w świetle danych o zapadalności i umieralności. Przegl Epidemiol. 2011; 65: 75-9.
5. Bidziński M, Dańska-Bidzińska A. Chirurgiczne leczenie raka szyjki macicy. Ginekol Pol. 2007; 78: 723-6.
6. Benedetti-Panici P, Greggi S, Colombo A et al. Neoadjuvant chemotherapy and radical surgery versus exclusive radiotherapy in locally advanced squamous cell cervical cancer: results from the Italian multicenter randomized study. J Clin Oncol. 2002; 20(1): 179-88.
7. Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer Meta-analysis Collaboration. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomized trials. Eur J Cancer. 2003; 39(17): 2470-86.
8. Rydzewska L, Tierney J, Vale CL et al. Neoadjuvant chemotherapy plus surgery versus for cervical cancer. Cochrane Database Syst Rev. 2012; 12(12): CD007406.
9. Kenter G, Greggi S, Vergote I et al. Results from neoadjuvant chemotherapy followed by surgery compared to chemoradiation for stage Ib2-II b cervical cancer, EORTC 55994. J Clin Oncol. 2019; 37(15 suppl): 5503.
10. Gupta S, Maheshwari A, Parab P et al. Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial. J Clin Oncol. 2018; 36(16): 1548-55.

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