Spectacular efficacy of neoadjuvant chemotherapy in a patient with cervical cancer of IB2 grade according to FIGO 2009 Case report

Main Article Content

Kamila Kaźmierczak
Błażej Nowakowski
Joanna Kufel-Grabowska
Witold Cholewiński


The presented case report is an example of a spectacular effect of induction systemic treatment in a patient with locally advanced cervical cancer of IB2 grade according to FIGO 2009 (International Federation of Gynecologist and Obstetrician). The effect of induction chemotherapy (three series in paclitaxel/24 h + cisplatin regimen at an interval of three weeks) was the total metabolic response of the primary tumor and nodal lesions found in FDG-PET/CT (18F-fluorodeoxyglucose – positron emission tomography combined with computed tomography) as well as an image of total regression of the tumor in the obtained postoperative histopathological examination.

Article Details

How to Cite
Kaźmierczak K, Nowakowski B, Kufel-Grabowska J, Cholewiński W. Spectacular efficacy of neoadjuvant chemotherapy in a patient with cervical cancer of IB2 grade according to FIGO 2009. OncoReview [Internet]. 2020Jun.30 [cited 2020Oct.30];10(2(38):69-6. Available from: https://journalsmededu.pl/index.php/OncoReview/article/view/1070


1. International Agency for Research on Cancer – IARC, Gobocan 2012. Estimated cancer incidence, mortality and prevalence worldwide 2015. http://globocan.iarc.fr.
2. Wojciechowska U, Didkowska J. Zachorowania i zgony na nowotwory złośliwe w Polsce, Krajowy Rejestr Nowotworów, Centrum Onkologii – Instytut im. Marii Skłodowskiej-Curie. http://onkologia.org.pl/raporty (Access: 3.04.2020).
3. Markowska J, Mądry J. Zarys ginekologii onkologicznej. Vol. 1. Termedia, Poznań 2018: 622-30, 797-8, 736-8.
4. Nowakowski A, Kotarski J. Rak szyjki macicy w Polsce i na świecie w świetle danych o zapadalności i umieralności. Przegl Epidemiol. 2011; 65: 75-9.
5. Bidziński M, Dańska-Bidzińska A. Chirurgiczne leczenie raka szyjki macicy. Ginekol Pol. 2007; 78: 723-6.
6. Benedetti-Panici P, Greggi S, Colombo A et al. Neoadjuvant chemotherapy and radical surgery versus exclusive radiotherapy in locally advanced squamous cell cervical cancer: results from the Italian multicenter randomized study. J Clin Oncol. 2002; 20(1): 179-88.
7. Neoadjuvant Chemotherapy for Locally Advanced Cervical Cancer Meta-analysis Collaboration. Neoadjuvant chemotherapy for locally advanced cervical cancer: a systematic review and meta-analysis of individual patient data from 21 randomized trials. Eur J Cancer. 2003; 39(17): 2470-86.
8. Rydzewska L, Tierney J, Vale CL et al. Neoadjuvant chemotherapy plus surgery versus for cervical cancer. Cochrane Database Syst Rev. 2012; 12(12): CD007406.
9. Kenter G, Greggi S, Vergote I et al. Results from neoadjuvant chemotherapy followed by surgery compared to chemoradiation for stage Ib2-II b cervical cancer, EORTC 55994. J Clin Oncol. 2019; 37(15 suppl): 5503.
10. Gupta S, Maheshwari A, Parab P et al. Neoadjuvant Chemotherapy Followed by Radical Surgery Versus Concomitant Chemotherapy and Radiotherapy in Patients With Stage IB2, IIA, or IIB Squamous Cervical Cancer: A Randomized Controlled Trial. J Clin Oncol. 2018; 36(16): 1548-55.

Most read articles by the same author(s)

Obs.: This plugin requires at least one statistics/report plugin to be enabled. If your statistics plugins provide more than one metric then please also select a main metric on the admin's site settings page and/or on the journal manager's settings pages.