House dust mites as factors allergenic
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Abstract
House dust mites are considered to be the most common cause of allergies and cases of asthma in our country. Recent studies indicate that dust mites produce more than 30 proteins with allergenic properties. Trigger IgE-mediated reactions by direct effects on IgE antibody synthesis and secretion of pro-inflammatory cytokines. The aim of this work was to analyze the concentrations of total IgE and specific antibodies to the house dust mite allergens. The percentage of the pathological IgE obtained in our studies has ranged between 80% and 96%. Studies have also shown that the levels of total IgE and specific IgE are influenced by the age of patients as well as concomitant diseases. The percentage of pathological IgE is higher than the value of the total IgE, which shows that not all patients concentrations of total IgE reaches values exceeding the reference range commensurate with sIgE. That is why it is important to complement the diagnosis of this allergy in patients with the normal levels of total IgE.
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
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