Regional deposition of mometasone furoate within the nasal cavity

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Bolesław Samoliński
Edyta Krzych-Fałta

Abstract



 

The effectiveness of nasal glucocorticoid therapy in the treatment of the inflammation of the nasal mucous membrane depends largely on the preparation used, type of carrier, method of application and thus the target site of drug deposition. Drug sedimentation is of particular importance because of the peculiar and highly diverse structure of the nasal cavity.


 

 



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How to Cite
Samoliński , B., & Krzych-Fałta , E. (2015). Regional deposition of mometasone furoate within the nasal cavity. Alergoprofil, 11(3), 5-8. Retrieved from https://journalsmededu.pl/index.php/alergoprofil/article/view/839
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References

1. Samoliński B., Arcimowicz M.: Patofizjologia nieżytów nosa. W: Samoliński B., Janczewski G. (red.): Nieżyty nosa, Warszawa 2000.
2. Shah S.A., Berger R.L., McDermontt J. et al.: Regional deposition of mometasone furoate nasal spray suspension in humans. Allergy Asthma Proc. 2015, 36: 48-57.
3. [http://ec.europa.eu/health/documents/community-register/2015/20150119130440/anx_130440_pl.pdf](wersja: 22.09.2015).
4. [https://www.doz.pl/leki/p3143-Nasonex] (wersja: 22.09.2015).
5. Newman S.P.: Characteristics of radiolabelled versus unlabelled inhaler formulations. J. Aerosol. Med. 1996, 9(suppl. 1): S37-47.
6. Laube B.L.: Devices for aerosol delivery to treat sinusitis. J. Aerosol. Med. 2007, 20: S5-S17; discussion: S17-S18.
7. Vidgren M.T., Kublik H.: Nasal delivery systems and their effect on deposition and absorption. Adv. Drug Deliv. Rev. 1998, 29(1-2): 157-177.
8. Kimbell J.S., Segal R.A., Asgharian B. et al.: Characterization of deposition from nasal spray devices using a computational fluid dynamics model of the human nasal passages. J. Aerosol. Med. 2007, 20(1): 59-74.