Hypoallergic dog – fact or fiction?
Article Sidebar
Published:
Jun 30, 2015
Keywords:
allergy to dog, major allergens, epidemiology, diagnosis
Main Article Content
Abstract
Prevalence of dogs and the contact with a dog in your immediate environment is often the cause of respiratory allergy. In order to minimize this risk, breeders presented dog breeds that would not cause allergic reactions. In this way appeared the concept of “hypoallergenic dog”. This article discusses the dog allergens, diagnostic options and evidence that there is no data for the classification of certain dog breeds as being “hypoallergenic”.
Downloads
Download data is not yet available.
Article Details
How to Cite
Kraus-Kolon , H., & Gawlik , R. (2015). Hypoallergic dog – fact or fiction?. Alergoprofil, 11(2), 34-40. Retrieved from https://journalsmededu.pl/index.php/alergoprofil/article/view/835
Issue
Section
Article
Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
References
1. Vredegoor D.W., Willemse T., Chapman M.D. et al.: Can f1 levels in hair and homes of different dog breeds: Lack of evidence to describe any dog breed as hypoallergenic. J. Allergy Clin. Immunol. 2012, 130: 904-909.
2. Heinzerling L., Frew A.J., Bindslev-Jensen C. et al.: Standart skin prick testing and sensitization to inhalant allergens across Europe – a survey from the GA2LEN network. Allergy 2005, 60: 1287-1300.
3. Ramadour M., Guetat M., Guetat J. et al.: Dog factor differences in Can f1 allergen production. Allergy 2005, 60: 1060-1064.
4. Rönmark E., Perzanowski M., Platts-Mills T. et al.: Four-year incidience of allergic sensitization among schoolchildren in a community where allergy to cat and dog dominates sensitization: Report from the Obstructive Lung Disease in Northern Sweden Study Group. J. Allergy Clin. Immunol. 2003, 112: 747-754.
5. Tubiolo V.C., Beall G.N.: Dog allergy: understanding our “best friend”? Clin. Exp. Allergy 1997, 27: 354-357.
6. Heutelbeck A.R., Schulz T., Bergmann K.C. et al.: Environmental exposure to allergens of different dog breeds and relevance in allergological diagnostics. J. Toxicol. Environ. Health A. 2008, 71: 751-758.
7. Arbes S., Cohn R., Yin M. et al.: Dog allergen (Can f1) and Cat allergen (Fel d1) in US homes: results from the national survey of lead and allergens housing. J. Allergy Clin. Immunol. 2004, 114: 111-117.
8. Zahradnik E., Raulf M.: Animal allergens and their presence in the environment. Frontiers in Immunol. 2014 [https://doi.org/10.3389/fimmu.2014.00076].
9. Nicholas Ch., Wegienka G., Havstad S. et al.: Dog characteristics and dog allergen levels in the home. Ann. Allergy Asthma Immunol. 2010, 105: 228-233.
10. Konieczny A., Morgenstern J.P., Bizinkauskas C.B. et al.: The major dog allergens, Can f1 and Can f2, are salivary lipocain proteins: cloning and immunological characterization of the recombinant forms. Immunology 1997, 92: 577-586.
11. Gawlik R.: Charakterystyka wybranych alergenów zwierząt. Alergia 2008, 4: 18-20.
12. Kamata Y., Miyanomae A., Nakayama E. et al.: Characterization of dog allergens Can f1 and Can f2. 1. Preparation of their recombinant proteins and antibodies. Int. Arch. Allergy Immunol. 2007, 142: 291-300.
13. Lockey R.T., Ledford D.: Allergens and allergen immunotherapy: subcutaneous, sublingual and oral. 5th edition. Taylor and Francis Group 2014, 224-225.
14. Obando S.U., Dominguez J.S.: Clinical impact of molecular diagnosis in dog allergy. Clinical and Translational Allergy 2014, 4: P52 [http://www.ctajournal.com/content/4/S2/P52].
15. Polovic N., Waden K., Binnmyr J. et al.: Dog saliva – an important source of dog allergens. Allergy 2013, 68: 585-592.
16. Rudzki E.: Alergeny. Medycyna Praktyczna, Kraków 2008, 256-259.
17. Konradsen J.R, Fujisawa T., Hage M. et al.: Allergy to furry animals: New insights, diagnostic approaches and challenges. J. Allergy Clin. Immunol. 2014 [https://doi.org/10.1016/j.jaci.2014.08.026].
18. Mattsson L., Lundgren T., Olsson P. et al.: Molecular and immunological characterization of Can f4: a dog dander allergen cross-reactive with a 23 kDa odorant-binding protein in cow dander. Clin. Exp. Allergy 2010, 40: 1276-1287.
19. Mattsson L., Lundgren T., Eveberg H. et al.: Prostatic kallikrein: a new major dog allergen. J. Allergy Clin. Immunol. 2009, 123: 362-368.
20. Nilsson O.B., Binmyr J., Zoltowska A. et al.: Characterization of the dog lipocalin allergen Can f6: the role in cross-reactivity with cat and horse. Allergy 2012, 67: 751-757.
21. Lutsky I., Fink J.N., Arkins J.A. et al.: Skin test reactivity to dog-derived antigens. Clin. Allergy 1980, 10: 331-340.
22. Lindgren S., Belin L., Dreborg S. et al.: Breed – specific dog – dandruff allergens. J. Allergy Clin. Immunol. 1988, 82: 196-204.
23. Nicholas C., Wegienka G., Havstad S. et al.: Dog allergen levels in homes with hypoallergenic compared with nonhypoalergenic dogs. Am. J. Rhinol. Allergy. 2011, 25: 252-256.
24. Lombardi E., Simoni M., La Grutta S. and the SIDRIA Collaborative Group: Effect of pet exposure in the first year of life on respiratory and allergic symptoms in 7-year-old children. The SIDRIA study. Pediatr. Allergy Immunol. 2010, 21: 268-276.
25. Gern J.E., Reardon C.L., Hoffjan S. et al.: Effects of dog ownership and genotype on immune development and atopy in infancy. Allergy Clin. Immunol. 2004, 113: 307-314.
26. Bufford J.D., Reardon C.L., Roberg K.A. et al.: Effects of dog ownership in early childhood on immune development and atopic diseases. Clin. Exp. Allergy 2008, 38: 1635-1643.
27. Chen C.M., Tisher C., Schnappienger M. et al.: The role of cats and dogs in asthma and allergy – a systematic review. Int. J. Hyg. Environ. Health 2010, 213: 1-31.
28. Mandhane P.J., Sears M.R., Poulton R. et al.: Cats and dogs and risk of atopy in childhood and adulthood. J. Allergy Clin. Imunol. 2009, 124: 745-750.
29. Butt A., Rashid D., Lockey R.: Do hypoallergenic cats and dogs exist? Ann. Allergy and Asthma Immunol. 2012, 108: 74-76.
30. Hodson T., Custovic A., Simpson A. et al.: Washing the dog reduces dog allergens levels, but the dog needs to be washed twice a week. J. Allergy Clin. Immunol. 1999, 103: 581-585.
31. Coop C., Johnson T., Hagen L. et al.: Dog immunotherapy practices among allergists. The Internet Journal of Asthma Allergy and Immunol. 2006, 5 [http://ispub/IJAAI/5/2/10614].
32. Haugaard L., Dahl R.: Immunotherapy in patients allergic to cat and dog dander. I. Clinical results. Allergy 1992, 47: 249-254.
2. Heinzerling L., Frew A.J., Bindslev-Jensen C. et al.: Standart skin prick testing and sensitization to inhalant allergens across Europe – a survey from the GA2LEN network. Allergy 2005, 60: 1287-1300.
3. Ramadour M., Guetat M., Guetat J. et al.: Dog factor differences in Can f1 allergen production. Allergy 2005, 60: 1060-1064.
4. Rönmark E., Perzanowski M., Platts-Mills T. et al.: Four-year incidience of allergic sensitization among schoolchildren in a community where allergy to cat and dog dominates sensitization: Report from the Obstructive Lung Disease in Northern Sweden Study Group. J. Allergy Clin. Immunol. 2003, 112: 747-754.
5. Tubiolo V.C., Beall G.N.: Dog allergy: understanding our “best friend”? Clin. Exp. Allergy 1997, 27: 354-357.
6. Heutelbeck A.R., Schulz T., Bergmann K.C. et al.: Environmental exposure to allergens of different dog breeds and relevance in allergological diagnostics. J. Toxicol. Environ. Health A. 2008, 71: 751-758.
7. Arbes S., Cohn R., Yin M. et al.: Dog allergen (Can f1) and Cat allergen (Fel d1) in US homes: results from the national survey of lead and allergens housing. J. Allergy Clin. Immunol. 2004, 114: 111-117.
8. Zahradnik E., Raulf M.: Animal allergens and their presence in the environment. Frontiers in Immunol. 2014 [https://doi.org/10.3389/fimmu.2014.00076].
9. Nicholas Ch., Wegienka G., Havstad S. et al.: Dog characteristics and dog allergen levels in the home. Ann. Allergy Asthma Immunol. 2010, 105: 228-233.
10. Konieczny A., Morgenstern J.P., Bizinkauskas C.B. et al.: The major dog allergens, Can f1 and Can f2, are salivary lipocain proteins: cloning and immunological characterization of the recombinant forms. Immunology 1997, 92: 577-586.
11. Gawlik R.: Charakterystyka wybranych alergenów zwierząt. Alergia 2008, 4: 18-20.
12. Kamata Y., Miyanomae A., Nakayama E. et al.: Characterization of dog allergens Can f1 and Can f2. 1. Preparation of their recombinant proteins and antibodies. Int. Arch. Allergy Immunol. 2007, 142: 291-300.
13. Lockey R.T., Ledford D.: Allergens and allergen immunotherapy: subcutaneous, sublingual and oral. 5th edition. Taylor and Francis Group 2014, 224-225.
14. Obando S.U., Dominguez J.S.: Clinical impact of molecular diagnosis in dog allergy. Clinical and Translational Allergy 2014, 4: P52 [http://www.ctajournal.com/content/4/S2/P52].
15. Polovic N., Waden K., Binnmyr J. et al.: Dog saliva – an important source of dog allergens. Allergy 2013, 68: 585-592.
16. Rudzki E.: Alergeny. Medycyna Praktyczna, Kraków 2008, 256-259.
17. Konradsen J.R, Fujisawa T., Hage M. et al.: Allergy to furry animals: New insights, diagnostic approaches and challenges. J. Allergy Clin. Immunol. 2014 [https://doi.org/10.1016/j.jaci.2014.08.026].
18. Mattsson L., Lundgren T., Olsson P. et al.: Molecular and immunological characterization of Can f4: a dog dander allergen cross-reactive with a 23 kDa odorant-binding protein in cow dander. Clin. Exp. Allergy 2010, 40: 1276-1287.
19. Mattsson L., Lundgren T., Eveberg H. et al.: Prostatic kallikrein: a new major dog allergen. J. Allergy Clin. Immunol. 2009, 123: 362-368.
20. Nilsson O.B., Binmyr J., Zoltowska A. et al.: Characterization of the dog lipocalin allergen Can f6: the role in cross-reactivity with cat and horse. Allergy 2012, 67: 751-757.
21. Lutsky I., Fink J.N., Arkins J.A. et al.: Skin test reactivity to dog-derived antigens. Clin. Allergy 1980, 10: 331-340.
22. Lindgren S., Belin L., Dreborg S. et al.: Breed – specific dog – dandruff allergens. J. Allergy Clin. Immunol. 1988, 82: 196-204.
23. Nicholas C., Wegienka G., Havstad S. et al.: Dog allergen levels in homes with hypoallergenic compared with nonhypoalergenic dogs. Am. J. Rhinol. Allergy. 2011, 25: 252-256.
24. Lombardi E., Simoni M., La Grutta S. and the SIDRIA Collaborative Group: Effect of pet exposure in the first year of life on respiratory and allergic symptoms in 7-year-old children. The SIDRIA study. Pediatr. Allergy Immunol. 2010, 21: 268-276.
25. Gern J.E., Reardon C.L., Hoffjan S. et al.: Effects of dog ownership and genotype on immune development and atopy in infancy. Allergy Clin. Immunol. 2004, 113: 307-314.
26. Bufford J.D., Reardon C.L., Roberg K.A. et al.: Effects of dog ownership in early childhood on immune development and atopic diseases. Clin. Exp. Allergy 2008, 38: 1635-1643.
27. Chen C.M., Tisher C., Schnappienger M. et al.: The role of cats and dogs in asthma and allergy – a systematic review. Int. J. Hyg. Environ. Health 2010, 213: 1-31.
28. Mandhane P.J., Sears M.R., Poulton R. et al.: Cats and dogs and risk of atopy in childhood and adulthood. J. Allergy Clin. Imunol. 2009, 124: 745-750.
29. Butt A., Rashid D., Lockey R.: Do hypoallergenic cats and dogs exist? Ann. Allergy and Asthma Immunol. 2012, 108: 74-76.
30. Hodson T., Custovic A., Simpson A. et al.: Washing the dog reduces dog allergens levels, but the dog needs to be washed twice a week. J. Allergy Clin. Immunol. 1999, 103: 581-585.
31. Coop C., Johnson T., Hagen L. et al.: Dog immunotherapy practices among allergists. The Internet Journal of Asthma Allergy and Immunol. 2006, 5 [http://ispub/IJAAI/5/2/10614].
32. Haugaard L., Dahl R.: Immunotherapy in patients allergic to cat and dog dander. I. Clinical results. Allergy 1992, 47: 249-254.