Innovative solution for the treatment of alllergic rhinitis
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Abstract
Allergic rhinitis is a frequent noninfectious disease of upper respiratory tract. For many sufferers it is a serious health problem causing inconvenience in everyday life. Treatment of serious form of disease, with intensified clinical symptoms, is a challenge. Lack of patient’s compliance rising from the necessity of taking more than one drug at a time, is also a problem. The aim of therapy in allergic rhinitis is removing local symptoms by local blocking of allergic reaction as well as complex treatment, together with elements of prophylaxis. From the practical point of view the application of antihistaminic agents (nasal and oral) parallel to nasal steroids seems to be appropriate. It is especially important in patients with intensified allergic symptoms, accompanied with oedema of nasal mucosa, leading to nasal blockade. The application of nasal steroids as the only agent in patients with intensified allergic symptoms do not guarantee immediate relief and may lead to poor patient’s compliance. The combination of azelastine and propionate fluticasone gained a very good grades in clinical studies. Treatment with the combination form allowed to achieve the decrease in total symptoms score in patients with allergic rhinitis 7 days earlier than traditional treatment. Both moderate and severe forms of allergic rhinitis were better controlled with the combination form than with traditional treatment.
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
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