The influence of the isotonic solution of sea water (Marimer) application on allergic symptoms and nasal mucosa in allergic rhinitis sufferers sensitised to pollen allergens
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Abstract
The basis of allergic rhinitis treatment is the reduction of the contact of nasal mucosa with allergens. The hypothesis proposed by the authors of this study is that in a group of patients using an isotonic solution of sea water (Marimer, Laboratoires GILBERT, France) in addition to standard treatment with antihistamines and intranasal steroids the symptoms of allergy should be diminished compared to a group of patients treated with antihistamines and intranasal steroids only. The study embraced 106 patients with persistentallergic rhinitis due to house dust mites allergens hipersensitivity. The patients were divided into 3 groups: group I – patients receiving antihistaminics and topical nasal steroids, group II – patients receiving, besides above mentioned drugs, additionally cromoglicans, group III – patients receiving, besides above mentioned drugs, additionally Marimer preparation. The lower incidence of symptoms assessed in the form of symptoms score card and rhinologic examination was recorded in group III – patients receiving the isotonic solution of sea water (Marimer) as pharmacological treatment adjunct. Nasal washing with the isotonic solution of sea water seems to be a valuable supplement of the pharmacological treatment of allergic rhinitis.
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Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
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