Autumn season and difficult cases of allergy sufferers in whom it is worth using ebastine Review article

Abstract

Many environmental factors in autumn and winter increase the severity of allergic rhinitis. To effectively treat allergic symptoms, you need to have an effective and safe second-generation antihistamine in your arsenal. Ebastine is one such drug. It is a prodrug quickly metabolized by the liver to an active metabolite – cerebastine. It is a strong, highly selective histamine H₁ receptor antagonist with a prolonged effect. This substance does not exhibit anticholinergic effects. Ebastine is a well-studied second-generation antihistamine with a very good safety and efficacy profile. It is the first-line drug in the treatment of allergic rhinitis and urticaria. Below are four typical cases of patients in whom it is worth using ebastine. Classic patients who may have treatment of allergic diseases with this drug included are: patients requiring higher doses (in the absence of effectiveness of standard doses and severe symptoms of allergic rhinitis or urticaria), patients expecting a quick effect, convenient, easy dosing and taking the drug, and people with coexisting cardiological problems, especially hypertension and heart rhythm disorders. Ebastine has a well-established place in the treatment of allergic rhinitis and urticaria in patients over 12 years of age.