Pazopanib in clear cell sarcoma therapy Case report

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Published: Mar 14, 2018
DOI: https://doi.org/10.24292/01.OR.140318
Keywords:
soft-tissue sarcoma, clear cell sarcoma, pazopanib

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Katarzyna Kryszczyszyn-Musialik
1. Oncology Department with Hematological Subdivision, Provincial Specialist Hospital No. 3 in Rybnik. 2. Chair and Department of Environmental Medicine and Epidemiology, Medical University of Silesia in Katowice
Grzegorz Słomian
Oncology Department with Hematological Subdivision, Provincial Specialist Hospital No. 3 in Rybnik

Abstract

Clear cell sarcoma (CCS) is a rare soft-tissue sarcoma and is characterized by a translocation t(12;22) (q13;q12). Because of some similarities to maligned melanoma it is called melanoma of soft parts. CCS has characteristic clinical features. It is commonly reported in young adults as slowly growing tumor followed by aggressive course. Its features are: regional lymph node spread and tendency for local recurrence and a propensity for pulmonary metastasis. Metastatic CCS is a very aggressive disease with pure prognosis. Conventional chemotherapy has little role to play in the management of CCS. The article presents the case of a patient with metastatic CCS with massive lung dissemination, metastatic in liver, left adrenal, pelvis and superficial soft tissue. In patient pazopanib therapy resulted in nine-month control of the disease.

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How to Cite
1.
Kryszczyszyn-Musialik K, Słomian G. Pazopanib in clear cell sarcoma therapy. OncoReview [Internet]. 2018Mar.14 [cited 2024Nov.22];8(1(29):24-7. Available from: https://journalsmededu.pl/index.php/OncoReview/article/view/418
Issue
Vol 8 No 1(29) (2018)
Section
QUALITY OF LIFE IN ONCOLOGY
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