Treatment of multiple superficial basal cell carcinomas with topical imiquimod Review article
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Abstract
Basal cell carcinoma is the most common malignancy of man. The use of the topical imiquimod 5% cream offers a noninvasive, nonsurgical, and an effective option for the treatment of primary types superficial basal cell carcinoma (sBCC). We present a case series of patients who used imiquimod 5% cream with good therapeutic effect. The medication had a good tolerability profile and there were no ocular adverse events. Imiquimod 5% cream could be considered the first choice treatment for BCCs in older patients who are poor candidates to surgery.
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Copyright: © Medical Education sp. z o.o. This is an Open Access article distributed under the terms of the Attribution-NonCommercial 4.0 International (CC BY-NC 4.0). License (https://creativecommons.org/licenses/by-nc/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)
References
2. Hassan I, Abid K, Mashkoor A, Qazi M. Bazex syndrome – a case report. N Dermatol Online 2011; 2: 18-20.
3. Vikram KM, Pushpinder SCh, Karaninder SM, Vikas S. Favre-Racouchot Syndrome. Our Dermatol Online 2013; 4: 328-329.
4. Molina AL, Mejía M, Restrepo R. [Congenital and multiple basal cell carcinoma]. Rev Asoc Colomb Dermatol 2011; 19: 85-88.
5. Martínez Braga G, Riveros R, Di Martino Ortiz B et al. [Dermatoscopy: contribution as a method to define surgical margins in basal cell carcinomas of the face, neck and trunk]. Our Dermatol Online 2013; 4: 28-31.
6. Abdulaziz A., Brzezinski P., Chiriac A. Skin of sailor: Cutis rhomboidalis nuchae, actinic keratosis, squamous cell carcinoma and basal cell carcinoma. Case report. OncoReview 2014; 1: A36-A40.
7. Lezcano L, Di Martino Ortiz B, Rodriguez Masi M et al. [Bowen’s disease treated with cryotherapy combined with topical 5% imiquimod. Alternative treatment to surgery in elderly patients with co-morbidities]. N Dermatol Online 2011; 2: 61-64.
8. Schmitt AR, Bordeaux JS. Solar keratoses: photodynamic therapy, cryotherapy, 5-fluorouracil, imiquimod, diclofenac, or what? Facts and controversies. Clin Dermatol 2013; 31: 712-717.
9. Schulze HJ, Cribier B, Requena L et al. Imiquimod 5% cream for the treatment of superficial basal cell carcinoma: results from a randomized vehicle-controlled phase III study in Europe. Br J Dermatol 2005; 152: 939-947.
10. Schön M, Bong AB, Drewniok C et al. Tumor-selective induction of apoptosis and the small-molecule immune response modifier imiquimod. J Natl Cancer Inst 2003; 95: 1138-1149.
11. Arits AH, Mosterd K, Essers BA et al. Photodynamic therapy versus topical imiquimod versus topical fluorouracil for treatment of superficial basal-cell carcinoma: a single blind, non-inferiority, randomised controlled trial. Lancet Oncol 2013; 14: 647-654.