Primary cutaneous B-cell lymphoma located on the face and hard palate Case report

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Piotr Brzeziński
Anca Chiriac
Radu Budurca
Anca E. Chiriac
Tudor Pinteala
Luminita Ivan
Liliana Foia

Abstract

Introduction: Primary cutaneous B-cell lymphomas represent primary cutaneous lymphomas. The World Health Organization-European Organization for Research and Treatment of Cancer defines primary cutaneous B-cell limphomas as malignant lymphomas that are confined to the skin at presentation after complete staging procedures.


Case report: We report a case of a woman with a cutaneous nodular B-cell lymphoma of the face, with very slow evolution that could easily be misdiagnosed. The patient had two non-ulcerated nodules on the left part of the face. A histological examination on both pieces following surgical excision showed a diffuse infiltrate of atypical B cells. The patient was subsequently directed to the Oncology Department for further investigation, but she died 24 hours afterwards due to one of the acute possible complications of the disease: pulmonary embolism.


Conclusion: Cutaneous B-cell lymphoma is an unusual and rare skin neoplasm with a great range of clinical presentations and this is an alarm sign for apparent common skin lesion.

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How to Cite
1.
Brzeziński P, Chiriac A, Budurca R, Chiriac AE, Pinteala T, Ivan L, Foia L. Primary cutaneous B-cell lymphoma located on the face and hard palate. OncoReview [Internet]. 2014Sep.30 [cited 2024Apr.29];4(3(15):113-6. Available from: https://journalsmededu.pl/index.php/OncoReview/article/view/369
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References

1. Thomas BR, Whittaker S. A practical approach to accurate classification and staging of mycosis fungoides and Sézary syndrome. Skin Therapy Lett 2012; 17: 5-9.
2. Willemze R, Jaffe ES, Burg G et al. WHO-EORTC classification of cutaneous lymphomas. Blood 2005; 105: 3768-3785.
3. Fink-Puches R, Zenahlik P, Bäck B et al. Primary cutaneous lymphomas: applicability of current classification schemes (European Organization for Research and Treatment of Cancer, World Health Organization) based on clinicopathologic features observed in a large group of patients. Blood 2002; 99: 800-805.
4. Hristov AC. Primary cutaneous diffuse large B-cell lymphoma, leg type: diagnostic considerations. Arch Pathol Lab Med 2012; 136: 876-881.
5. Brzeziński P, Wass J, White K et al. Dermatology eponyms phenomen/sign – Dictionary (A) –continued. N Dermatol Online 2011; 2: 27-34.
6. Brzeziński P, Sanaei-Zadeh H, Shane T et al. Dermatology eponym – phenomen/sign – Dictionary (B). N Dermatol Online 2011; 2: 35-45.
7. Abreu Velez AM, Klein AD, Howard MS. Skin appendageal immune reactivity in a case of cutaneous lupus. Our Dermatol Online 2011; 2: 175-180.
8. Abreu Velez AM, Jackson BL, Velasquez Cantillo KL et al. Merkel cell carcinoma versus metastatic small cell primary bronchogenic carcinoma. Our Dermatol Online 2013; 4: 64-71.
9. Oliveira A, Caetano M, Alves R, et al. Letter: Primary cutaneous marginal zone B cell lymphoma of the face: a challenging diagnosis. Dermatol Online J 2012; 18: 12.
10. Bandyopadhyay R, Bandyopadhyay SK, Dhua D et al. Primary cutaneous precursor B-cell lymphoblastic lymphoma with late dissemination. Singapore Med J 2011; 52: e258-261.