CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission Opis przypadku

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Opublikowane: mar 19, 2021
DOI: https://doi.org/10.24292/01.OT.300321.5
Słowa kluczowe:
lymphoproliferative, CD30, T-cell, conjunctival

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Paula Marticorena Álvarez
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0003-4817-7350
Guadalupe Garrido Ceca
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0002-3917-2446
Mercedes Guijarro Rojas
Department of Pathological Anatomy, Hospital Universitario La Princesa, Madrid, Spain

Abstrakt

Introduction: CD30-positive T-cell lymphoproliferative lesions represent a spectrum of heterogeneous disorders.


Clinical case: An incision biopsy was performed in a 25-year-old man with a lump in the bulbar conjunctiva. Immunohistochemistry indicated membrane positivity for CD3 and CD30 in over 75%. PCR identified the monoclonal nature of the T-cells. The hematological study was normal. Following biopsy, the conjunctival tumor diminished until disappear.


Conclusions: Mucosal CD30-positive T-cell lymphoproliferation could be ascribed to a reactive process but it is necessary to rule out a primary conjunctival tumor or the first manifestation of an anaplastic large cell lymphoma.

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1.
Marticorena Álvarez P, Garrido Ceca G, Guijarro Rojas M. CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission. Ophthatherapy [Internet]. 19 marzec 2021 [cytowane 22 lipiec 2024];8(1):45-8. Dostępne na: https://journalsmededu.pl/index.php/ophthatherapy/article/view/1176
Numer
Tom 8 Nr 1 (2021)
Dział
Terapie zachowawcze
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Bibliografia

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4. Clarke B, Legodi E, Chrystal V et al. Systemic anaplastic large cell lymphoma presenting with conjunctival involvement. Arch Ophthalmol. 2003; 121(4): 568-70.
5. Liu F, Li M, Zhang LY et al. Clinicopathologic features of primary mucosal CD30-positive T-cell lymphoproliferative disorders in head and neck region. Zhonghua Bing Li Xue Za Zhi. 2018; 47(6): 412-6.