CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission Case report

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Published: Mar 19, 2021
DOI: https://doi.org/10.24292/01.OT.300321.5
Keywords:
lymphoproliferative, CD30, T-cell, conjunctival

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Paula Marticorena Álvarez
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0003-4817-7350
Guadalupe Garrido Ceca
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0002-3917-2446
Mercedes Guijarro Rojas
Department of Pathological Anatomy, Hospital Universitario La Princesa, Madrid, Spain

Abstract

Introduction: CD30-positive T-cell lymphoproliferative lesions represent a spectrum of heterogeneous disorders.


Clinical case: An incision biopsy was performed in a 25-year-old man with a lump in the bulbar conjunctiva. Immunohistochemistry indicated membrane positivity for CD3 and CD30 in over 75%. PCR identified the monoclonal nature of the T-cells. The hematological study was normal. Following biopsy, the conjunctival tumor diminished until disappear.


Conclusions: Mucosal CD30-positive T-cell lymphoproliferation could be ascribed to a reactive process but it is necessary to rule out a primary conjunctival tumor or the first manifestation of an anaplastic large cell lymphoma.

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How to Cite
1.
Marticorena Álvarez P, Garrido Ceca G, Guijarro Rojas M. CD30-positive T-cell lymphoproliferation of the bulbar conjuntival mucosa showing spontaneous remission. Ophthatherapy [Internet]. 2021Mar.19 [cited 2024Nov.24];8(1):45-8. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/1176
Issue
Vol 8 No 1 (2021)
Section
Conservative treatment
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