The pharmacotherapy of treatment-resistant depression Review article

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Tadeusz Parnowski

Abstract

For over 40 years researchers are trying to understand what does treatment resistance in depression means. New definitions, staging methods in treatment do not decrease numbers of treatment-resistant patients, which might suggest influence of other factors, such as false diagnosis, inadequate treatment, psychosocial factors. Current strategies of treatment include use of new biological methods or drugs with different mechanisms. Assessment of efficacy and safety glutamatergic drugs and dopamine agonists seems to be important in context add-on treatment or monotherapy.

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References

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