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The adaptive optics (AO) technology has become a valuable diagnostic tool in vision research for studying retinal microscopic structure and function. It is an infrared adaptive optics retinal camera that allows non-invasive visualization of cone photoreceptor cells, the retinal vessel wall and lumen diameter, nerve fibers, and structure of lamina cribrosa, that remain invisible with other current diagnostic techniques. The AO technology may provide information about the pathologic changes in the retina, even in the absence of structural or functional abnormalities in the current diagnostic imaging. The rtx1TM (Imagine Eyes, France) is the only AO imaging device that has received regulatory clearance for ophthalmic examinations in multiple countries. In this article we present a brief overview of AO development, and its evolving range of applications in ophthalmic diagnostics.
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