Comparison of the sensitivity of the BMO-MRW, GCC, ONH and RNFL methods in the diagnosis and treatment evaluation of juvenile glaucoma Original research study

Article Sidebar

PDF PDF (Język Polski)


Published: Dec 30, 2021
DOI: https://doi.org/10.24292/01.OT.301221
Keywords:
juvenile glaucoma, BMO-MRW, GCC, ONH, RNFL, comparison of diagnostic sensivity

Main Article Content

Marek Edmund Prost
1. Department of Ophthalmology, Military Institute of Aviation Medicine, Warsaw. 2. Centre for Pediatric Ophthalmology, Warsaw, Poland
http://orcid.org/0000-0002-5620-4171

Abstract

BMO-MRW is a new SOCT parameter that has been introduced in recent years in the diagnosis of glaucomatous damage to optic retinal nerve fibers on the optic disc.


The aim of this study is to compare the sensitivity of this method with other methods used to evaluation of the retinal nerve fibres damage in patients with juvenile glaucoma.


The study was conducted in 20 patients with juvenile glaucoma, aged 5–16 years. In all of them, the degree of retinal nerve fibers damage was measured using BMO-MRW, GCC, ONH and RNFL methods. The examinations were  performed every 3 months during a 1.5-year follow-up of these patients.


The results of these studies indicate that the most sensitive method of the degree of retinal nerve fibers damage in juvenile glaucoma is GCC and BMO-MRW, the less sensitive RNFL and at least sensitive is the ONH method.

Downloads

Download data is not yet available.

Article Details

How to Cite
1.
Prost ME. Comparison of the sensitivity of the BMO-MRW, GCC, ONH and RNFL methods in the diagnosis and treatment evaluation of juvenile glaucoma. Ophthatherapy [Internet]. 2021Dec.30 [cited 2024Dec.22];8(4):217-23. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/1547
Issue
Vol 8 No 4 (2021)
Section
Diagnostics
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Copyright: © Medical Education sp. z o.o. License allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.

Address reprint requests to: Medical Education, Marcin Kuźma (marcin.kuzma@mededu.pl)

References

1. Allinghama RR, Liub Y, Rheec DJ. The genetics of primary open-angle glaucoma: A review. Exp Eye Res. 2009; 88: 837-44.
2. Quigley HA, Dunkelberger GR, Green WR. Retinal ganglion cell atrophy correlated with automated perimetry in human eyes with glaucoma. Am J Ophthalmol. 1989; 107: 453-64.
3. Prost M, Wasyluk J. Histopatologia uszkodzenia komórki zwojowej siatkówki a diagnostyka i monitorowanie progresji jaskry. Ophthatherapy. 2017; 4(1): 36-41.
4. Gardiner SK, Ren R, Yang H et al. A method to estimate the amount of neuroretinal rim tissue in glaucoma: Comparison with current methods for measuring rim area. Am J Ophthalmol. 2014; 157: 540-9.
5. Park K-H, Lee L-W, Kim J-M et al. Bruch’s membrane opening-minimum rim width and visual field loss in glaucoma: a broken stick analysis. Int J Ophthalmol. 2018; 11: 828-34.
6. Cho H-K, Kee C. Rate of change in Bruch’s Membrane Opening-Minimum Rim Width and peripapillary RNFL in early normal tension glaucoma. J Clin Med. 2020; 9: 1-13.
7. Bambo MP, Fuentemilla E, Cameo B et al. Diagnostic capability of a linear discriminant function applied to a novel Spectralis OCT glaucoma- detection Protocol. BMC Ophthalmology. 2020; 20(35): 1-8.
8. Chauhan BC, O’Leary N, Al Mobarak FA et al. Enhanced detection of open-angle glaucoma with an anatomically accurate optical coherence tomography-derived neuroretinal rim parameter. Ophthalmology. 2013; 120: 535-43.
9. Park DY, Lee DJ, Han JC et al. Applicability of ISNT Rule Using BMO-MRW to Differentiate Between Healthy and Glaucomatous Eyes. J Glaucoma. 2018; 27: 610-6.
10. Park K, Kim J, Lee J. The relationship between Bruch’s Membrane Opening-Minimum Rim Width and Retinal Nerve Fiber Layer thickness and a new index using a neural network. TVST. 2018; 7(4): 1-17.
11. Pollet-Villard F, Chiquet C, Romanet J-P et al. Structure-function relationships with spectral domain optical coherence tomography retinal nerve fiber layer and optic nerve head measurements. Invest Ophthalmol Vis Sci. 2014; 55: 2953-62.
12. Mizumoto K, Gosho M, Zako M. Correlation between optic nerve head structural parameters and glaucomatous visual field indices. Clin Ophthalmol. 2014; 8: 1203-8.
13. Rebolleda E, Casado A, Oblanca N. The new Bruch’s Membrane Opening – Minimum Rim Width classification improves optical coherence tomography specificity in tilted discs. Clin Ophthalm. 2016; 10: 2417-25.
14. Park K-H, Lee J-W, Kim J-M et al. Bruch’s membrane opening-minimum rim width and visual feld loss in glaucoma: a broken stick analysis. J Clin Ophthalmol. 2018; 11: 828-34.
15. Gmeiner JMD, Schrems WA Mardin CY. Comparison of Bruch’smembrane opening minimum rim width and peripapillary retinal nerve fiber layer thickness in early glaucoma assessment. Invest Ophthalmol Vis Sci. 2016; 57: 575-84.
16. Li R, Wang X, Wei Y et al. Diagnostic capability of different morphological parameters for primary open‐angle glaucoma in the Chinese population. BMC Ophthalmology. 2021; 21(151): 1-9.
17. Zangalli CS, Reis ASC, Vianna JR et al. Interocular asymmetry of Minimum Rim Width and Retinal Nerve Fiber Layer thickness in healthy Brazilian individuals. J Glaucoma. 2018; 27: 1136-41.
18. Prost M. Przydatność różnych metod optycznej koherentnej tomografii w diagnostyce jaskry i ocenie jej progresji. Okulistyka. 2015; 2: 43-8.
19. Prost E, Szot M, Dudek D et al. Wiarygodność stosowania leków jako problem terapeutyczny w leczeniu jaskry w Polsce. Okulistyka. 2009; 1: 26-9.