The potential usage of D2 dopaminergic agonists in the treatment of VEGF-related eye diseases Review article

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Maciej Osęka
Katarzyna Saładziak
Agnieszka Jamrozy-Witkowska
Jacek Dziedziak
Agnieszka Cudnoch-Jędrzejewska
Anna Święch


Dopamine and D2 dopaminergic agonists inhibit endothelial growth factor (VEGF). This effect has been proven in many types of cancer and in ovarian hyperstimulation syndrome. Experimental studies indicate the potential use of these substances in the treatment of eye diseases with increased VEGF release, such as exudative AMD, diabetic macular edema and proliferative diabetic retinopathy. This paper presents a review of the latest literature on the potential use of D2 dopaminergic agonists in the treatment of vascular endothelial growth factor (VEGF) related diseases.

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Osęka M, Saładziak K, Jamrozy-Witkowska A, Dziedziak J, Cudnoch-Jędrzejewska A, Święch A. The potential usage of D2 dopaminergic agonists in the treatment of VEGF-related eye diseases. Ophthatherapy [Internet]. 2020Mar.31 [cited 2020Nov.30];7(1):36-9. Available from:
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