Infections prophylaxis after cataract surgery: fluroquinolones and anti-inflammatory drugs – alone or in combined medications? Review article

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Justyna Izdebska
Marta Wróblewska
Agnieszka Piechal
Marta Misiuk-Hojło


Cataract surgery is one of the most commonly performed medical procedures. Currently, the most commonly used antibacterials after ophthalmic surgery are moxifloxacin and levofloxacin. Of the steroidal anti-inflammatory drugs, loteprednol etabonate or dexamethasone phosphate are commonly used. Due to the fact that the current guidelines recommend different durations of use of fluorquinolones (1–2 weeks) and glucocorticosteroids (3–4 weeks) in patients after cataract surgery, it seems justified to administer these drugs in separate preparations currently available on the market. There is a concern that the use of combination preparations may cause the patient to take fluoroquinolone for too long to maintain the anti-inflammatory effect of corticosteroids.
in the surgical site, and this may lead to the selection of resistant strains and increase the risk of adverse effects.


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Izdebska J, Wróblewska M, Piechal A, Misiuk-Hojło M. Infections prophylaxis after cataract surgery: fluroquinolones and anti-inflammatory drugs – alone or in combined medications?. Ophthatherapy [Internet]. 2023Jun.30 [cited 2024Jun.20];10(2):135-41. Available from:
Surgery and laser therapy


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