Infections prophylaxis after cataract surgery: fluroquinolones and anti-inflammatory drugs – alone or in combined medications? Review article

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Published: Jun 30, 2023
DOI: https://doi.org/10.24292/01.OT.220523.9
Keywords:
cataract surgeries, postoperative treatment, combined preparations

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Justyna Izdebska
Chair and Department of Ophthalmology, Faculty of Medicine, Medical University of Warsaw
http://orcid.org/0000-0002-5289-6860
Marta Wróblewska
Department of Dental Microbiology, Faculty of Medicine and Dentistry, Medical University of Warsaw
http://orcid.org/0000-0002-9126-7442
Agnieszka Piechal
Department of Experimental and Clinical Pharmacology, Centre for Preclinical Research and Technology, Medical University of Warsaw
http://orcid.org/0000-0002-0335-3288
Marta Misiuk-Hojło
Clinic of Ophthalmology, Medical University of Wroclaw, Poland
http://orcid.org/0000-0002-4020-3203

Abstract

Cataract surgery is one of the most commonly performed medical procedures. Currently, the most commonly used antibacterials after ophthalmic surgery are moxifloxacin and levofloxacin. Of the steroidal anti-inflammatory drugs, loteprednol etabonate or dexamethasone phosphate are commonly used. Due to the fact that the current guidelines recommend different durations of use of fluorquinolones (1–2 weeks) and glucocorticosteroids (3–4 weeks) in patients after cataract surgery, it seems justified to administer these drugs in separate preparations currently available on the market. There is a concern that the use of combination preparations may cause the patient to take fluoroquinolone for too long to maintain the anti-inflammatory effect of corticosteroids.
in the surgical site, and this may lead to the selection of resistant strains and increase the risk of adverse effects.

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How to Cite
1.
Izdebska J, Wróblewska M, Piechal A, Misiuk-Hojło M. Infections prophylaxis after cataract surgery: fluroquinolones and anti-inflammatory drugs – alone or in combined medications?. Ophthatherapy [Internet]. 2023Jun.30 [cited 2024May19];10(2):135-41. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/2803
Issue
Vol 10 No 2 (2023)
Section
Surgery and laser therapy
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