An unusual presentation of corneal intraepithelial neoplasia Case report

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Published: Dec 23, 2020
DOI: https://doi.org/10.24292/01.OT.311220.4
Keywords:
cornea, intraepithelial, neoplasia, epitheliectomy, interferon

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Paula Marticorena-Álvarez
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0003-4817-7350
Guadalupe Garrido Ceca
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0002-3917-2446
Diego Asensio Celdrán Vivancos
Department of Ophthalmology, Hospital Universitario La Princesa, Madrid, Spain
https://orcid.org/0000-0001-5018-0968

Abstract

Introduction: Conjunctival/corneal intraepithelial neoplasms are premalignant lesions usually showing conjunctival or limbal involvement. We report the rare case of an isolated corneal intraepithelial lesion.
Clinical case: An 80-year-old woman with an elevated, avascular, well-demarcated grey corneal plaque. After epitheliectomy and alcohol, the excised lesion was identified as a high-grade epithelial neoplasia. Treatment was topical interferon α-2b for 1 month without recurrences.
Conclusions: A well-defined greyish corneal opacity should always raise suspicion of an intraepithelial neoplasia. In the present case, epitheliectomy and topical recombinant interferon proved successful.

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How to Cite
1.
Marticorena-Álvarez P, Garrido Ceca G, Celdrán Vivancos DA. An unusual presentation of corneal intraepithelial neoplasia. Ophthatherapy [Internet]. 2020Dec.23 [cited 2024Dec.22];7(4):302-4. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/1119
Issue
Vol 7 No 4 (2020)
Section
Conservative treatment
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