Contact lenses as ophthalmic drug carriers
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Abstract
Contact lenses as drug carriers are an alternative for eye drops. Soaking lenses in drug solutions is ineffective, though, with most of the drug released form the lens within a few hours. There is a number of methods in use that increase the drug carrying capacity of contact lenses and prolong the drug’s release over time, including molecular imprinting, vitamin E diffusion barrier, co-polymerization with functional monomers, encapsulating nanoparticles in contact lenses, and generating drug nanodomains within the polymer matrix.
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