The role of the fixed-combination drugs in glaucoma treatment. Fixed-combination drugs versus monotherapy

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Małgorzata Karolczak-Kulesza
Sonia Pecold-Zielińska
Jarosław Kocięcki

Abstract

Glaucoma affects millions of individuals. This disease is one of the leading causes of blindness. Elevated intraocular pressure often associates with glaucoma progression. Nowadays, there are lots of therapeutic methods of glaucoma treatment, but topical therapy remains first choice treatment. In this article, the authors present how important role is multiple medications in the treatment of patients, when monotherapy is ineffective and insufficient in intraocular pressure reduction. The advantages of fixed-combination drugs – their effectiveness, tolerability, influence on chronic persistence and adherence have been analyzed. The attention was drawn to one of the novel fixed-combination drug (brimonidine + brinzolamide), the only one without β-blocker. It is really important for patients, for whom timolol therapy is contraindicated.

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1.
Karolczak-Kulesza M, Pecold-Zielińska S, Kocięcki J. The role of the fixed-combination drugs in glaucoma treatment. Fixed-combination drugs versus monotherapy. Ophthatherapy [Internet]. 2016Mar.31 [cited 2024Jul.3];3(1):13-7. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/588
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