The results of 3- and 6-month follow up in patients with dry AMD treated with 2RT laser
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Abstract
Bruch’s membrane thickening, which impairs nutrient and metabolite transport, constitutes the key aspect in the pathogenesis of age-related macular degeneration (AMD). As a result, the deposits (drusen) form between the retinal pigment epithelium (RPE) and Bruch’s membrane, causing degradation of both RPE and photoreceptor cells. It has been shown experimentally that pulse lasers may help decrease drusen size and improve metabolite transport through the Bruch’s membrane. Using a nanosecond pulse laser (2RT, Retinal Rejuvenation Therapy), operating at subthreshold energy levels, combines the beneficial laser effect with the prevention of laser-induced inflammation or photoreceptor damage. Below, we present the results of 2RTTM treatment in 610 patients with intermediate AMD, assessed at 3 and 6 months following treatment. The effect of treatment was assessed with Maia microperimetry (macular sensitivity assessment), optical coherence tomography (Spectralis HRA + OCT) as well as visual acuity and colour vision testing. Our findings included: an extreme improvement in macular sensitivity at 3 months following 2RT, with a subsequent decrease at 6 months, visual acuity improvements maintained at 6 months, yet without a correlation with OCT and colour vision improvement.
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