Floppy eyelid syndrome as an ocular condition associated with increased body mass index - classification, diagnostics and treatment Review article

Main Article Content

Paulina Szabelska
Wacław Ofman
Dominika Białas
Radosław Różycki
Joanna Gołębiewska

Abstract

Floppy eyelid syndrome is a common ophthalmic condition characterized by a sagging eyelid, which causes its spontaneous wrinkling during sleep. It can be a result of local and systemic diseases. A characteristic group of patients who suffer from floppy eyelid syndrome are middle-aged men with an increased body mass index. Obesity in this group of patients is recognized as the strongest risk factor for the occurrence of obstructive sleep apnea syndrome. The aim of the article is to review the diagnostic methods that are used in the case of floppy eyelid syndrome. The paper also discusses therapeutic methods including surgical techniques.

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How to Cite
1.
Szabelska P, Ofman W, Białas D, Różycki R, Gołębiewska J. Floppy eyelid syndrome as an ocular condition associated with increased body mass index - classification, diagnostics and treatment. Ophthatherapy [Internet]. 2022Dec.31 [cited 2024Nov.21];9(4):219-24. Available from: https://journalsmededu.pl/index.php/ophthatherapy/article/view/2171
Section
Diagnostics

References

1. Culbertson WW, Ostler HB. The floppy eyelid syndrome. Am J Ophthalmol. 1981; 92(4): 568-75. http://doi.org/10.1016/0002-9394(81)90652-8.
2. Karger RA, White WA, Park WC et al. Prevalence of floppy eyelid syndrome in obstructive sleep apnea hypopnea syndrome. Ophthalmology. 2006; 113(9): 1669-74. http://doi.org/10.1016/j.ophtha.2006.02.053.
3. Fowler AM, Dutton JJ. Floppy eyelid syndrome as a subset of lax eyelid conditions: relationships and clinical relevance (an ASOPRS thesis). Ophthalmic Plast Reconstr Surg. 2010; 26(3): 195-204. http://doi.org/10.1097/IOP.0b013e3181b9e37e.
4. Parunović A. Floppy eyelid syndrome. Br J Ophthalmol. 1983; 67(4): 264-6. http://doi.org/10.1136/bjo.67.4.264.
5. McNab AA. Floppy eyelid syndrome and obstructive sleep apnea. Ophthalmic Plast Reconstr Surg. 1997; 13(2): 98-114. http://doi.org/10.1097/00002341-199706000-00005.
6. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep. 1999; 22(5): 667-89.
7. Cho JH, Choi JH, Suh JD et al. Comparison of Anthropometric Data Between Asian and Caucasian Patients With Obstructive Sleep Apnea: A Meta-Analysis. Clin Exp Otorhinolaryngol. 2016; 9(1): 1-7. http://doi.org/10.21053/ceo.2016.9.1.1.
8. De Gregorio A, Cerini A, Scala A et al. Floppy eyelid, an under-diagnosed syndrome: a review of demographics, pathogenesis, and treatment. Ther Adv Ophthalmol. 2021; 13: 25158414211059247. http://doi.org/10.1177/25158414211059247.
9. Garvey JF, Pengo MF, Drakatos P et al. Epidemiological aspects of obstructive sleep apnea. J Thorac Dis. 2015; 7(5): 920-9. http://doi.org/10.3978/j.issn.2072-1439.2015.04.52.
10. Pedrotti E, Demasi CL, Bruni E et al. Prevalence and risk factors of eye diseases in adult patients with obstructive sleep apnoea: results from the SLE.E.P.Y cohort study. BMJ Open. 2017; 7(10): e016142. http://doi.org/10.1136/bmjopen-2017-016142.
11. Srijithesh PR, Aghoram R, Goel A et al. Positional therapy for obstructive sleep apnoea. Cochrane Database Syst Rev. 2019; 5(5): CD010990. http://doi.org/10.1002/14651858.CD010990.pub2.
12. Brown MD, Potter JW. Floppy eyelid syndrome: a case report and clinical review. J Am Optom Assoc. 1992; 63(5): 309-14.
13. Lauer SA. Floppy Eyelid Syndrome. American Academy of Ophthalmology, EyeWiki (access: 30.10.2022).
14. Sward M, Kirk C, Kumar S et al. Lax eyelid syndrome (LES), obstructive sleep apnea (OSA), and ocular surface inflammation. Ocul Surf. 2018; 16(3): 331-6. http://doi.org/10.1016/j.jtos.2018.04.003.
15. De Gregorio A, Pedrotti E, Stevan G et al. Floppy eyelid syndrome and ectropion improvement after 1 month of 0.03% Bimatoprost topical therapy. Am J Ophthalmol Case Rep. 2020; 20: 100938. http://doi.org/10.1016/j.ajoc.2020.100938.
16. Dutton JJ. Surgical management of floppy eyelid syndrome. Am J Ophthalmol. 1985; 99(5): 557-60. http://doi.org/10.1016/s0002-9394(14)77957-7.
17. Waldie AM, Francis IC, Coroneo MT et al. Floppy eyelid syndrome “plasty” procedure: Employment of a periosteal transposition flap for surgery of floppy eyelid syndrome. Clin Exp Ophthalmol. 2019; 47(7): 864-70. http://doi.org/10.1111/ceo.13560.